[PDF][PDF] Engineering tolerance using biomaterials to target and control antigen presenting cells
LH Tostanoski, EA Gosselin, CM Jewell - Discov. Med, 2016 - jewell.umd.edu
Autoimmune diseases occur when cells of the adaptive immune system incorrectly
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
Biomaterial strategies for selective immune tolerance: advances and gaps
ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …
approaches to these diseases target cell types and pathways that drive disease, but these …
Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance
Y Rui, HB Eppler, AA Yanes… - Advanced healthcare …, 2023 - Wiley Online Library
During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
Engineering immune tolerance with biomaterials
Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
Cell and biomaterial delivery strategies to induce immune tolerance
BL Scotland, JR Shaw, S Dharmaraj, N Caprio… - Advanced Drug Delivery …, 2023 - Elsevier
The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …
allergies, is steadily increasing. However, current therapeutic approaches are often non …
Biomaterial-based approaches to engineering immune tolerance
AE Emerson, EM Slaby, SC Hiremath… - Biomaterials Science, 2020 - pubs.rsc.org
The development of biomaterial-based therapeutics to induce immune tolerance holds great
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
Engineering vaccines and niches for immune modulation
Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Designing biomaterials for the treatment of autoimmune diseases
B Tang, X Xie, J Lu, W Huang, J Yang, J Tian… - Applied Materials …, 2024 - Elsevier
Autoimmune diseases (ADs) are a group of chronic relapsing inflammatory diseases that
cause great suffering to patients and increase the economic burden of society. However, the …
cause great suffering to patients and increase the economic burden of society. However, the …
Controlled delivery of immunomodulators from a biomaterial scaffold niche to induce a tolerogenic phenotype in human dendritic cells
S Srinivasan, JE Babensee - ACS biomaterials science & …, 2020 - ACS Publications
Engineering a regulatory phenotype in dendritic cells (DCs) is a potential approach to
circumvent an immune response against self-antigens in autoimmunity or alloantigens in …
circumvent an immune response against self-antigens in autoimmunity or alloantigens in …