The COPII coat complex found on endoplasmic reticulum (ER)-derived vesicles plays a
critical role in cargo selection. We now address the potential role of biosynthetic cargo in …

Vesicle trafficking from the endoplasmic reticulum (ER) is a vital cellular process in all
eukaryotes responsible for moving secretory cargoes from the ER to the Golgi apparatus. To …

Protein egress from the endoplasmic reticulum (ER) is driven by a conserved cytoplasmic
coat complex called the COPII coat. The COPII coat complex contains an inner shell …

Vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex constitutes the
initial step in protein secretion. COPII‐coated vesicles mediate the export of newly …

The first membrane trafficking step in the biosynthetic secretory pathway, the export of
proteins and lipids from the endoplasmic reticulum (ER), is mediated by COPII-coated …

The coat complex COPII forms vesicles at the endoplasmic reticulum to transport a variety of
cargo proteins to the Golgi structure. Recent biochemical and structural studies reveal the …

The coat protein complex II (COPII) generates transport vesicles that mediate protein
transport from the endoplasmic reticulum (ER). Recent structural and biochemical studies …

Background Export from the ER is an essential process driven by the COPII coat, which
forms vesicles at ER exit sites (ERESs) to transport mature secretory proteins to the Golgi …

Forward transport of proteins from the endoplasmic reticulum (ER) to the Golgi complex
depends on COPII, a membrane coat that forms ER-derived vesicles. Based on …

First discovered by genetic analysis of yeast secretion mutants, the evolutionarily conserved
vesicular coat protein II (COPII) complex is responsible for membrane transport from the …