Sympathetic nerve biology in essential hypertension

M Esler, M Rumantir, D Kaye… - Clinical and …, 2001 - Wiley Online Library
Although the importance of sympathetic nervous activation in the pathogenesis of essential
hypertension is well documented, the exact pathophysiology of the sympathetic nervous …

Sympathetic activation in the pathogenesis of hypertension and progression of organ damage

G Mancia, G Grassi, C Giannattasio, G Seravalle - Hypertension, 1999 - Am Heart Assoc
Although animal models of hypertension have clearly shown that high blood pressure is
associated with and is probably caused by an increase in sympathetic cardiovascular …

The sympathetic nervous system in the pathogenesis of hypertension.

KH Rahn, M Barenbrock, M Hausberg - Journal of hypertension …, 1999 - europepmc.org
There are now numerous studies demonstrating that essential hypertension is accompanied
by sympathetic activation. Using drugs which block cardiac sympathetic effects, it could be …

Increased regional sympathetic nervous activity in human hypertension: causes and consequences.

M Esler, G Lambert, G Jennings - Journal of hypertension …, 1990 - europepmc.org
Biochemical, electrophysiological, pharmacological and haemodynamic findings provide
evidence for the existence of sympathetic nervous system activation in some patients with …

The central nervous system and neurogenic hypertension

DJ Reis, N Doba - Progress in cardiovascular diseases, 1974 - Elsevier
It HAS LONG been proposed that the sympathetic nervous system may play a critical role in
initiating and/or sustaining the disease of essential hypertension. l-4 The long-standing …

Role of the sympathetic nervous system in human hypertension

G Grassi - Journal of hypertension, 1998 - journals.lww.com
Animal studies have shown conclusively that sympathetic neural factors are involved in the
development and/or maintenance of high blood pressure. Whether this is also the case for …

Biochemical evidence of sympathetic hyperactivity in human hypertension.

M Esler, C Ferrier, G Lambert, G Eisenhofer, H Cox… - …, 1991 - Am Heart Assoc
Radiotracer measures of norepinephrine overflow to plasma are well suited for studying
both human sympathetic nervous system responses to mental stress and sympathetic …

The sympathetic neurobiology of essential hypertension: disparate influences of obesity, stress, and noradrenaline transporter dysfunction?

M Esler, M Rumantir, D Kaye… - American journal of …, 2001 - academic.oup.com
Although the importance of sympathetic nervous activation in the pathogenesis of essential
hypertension is well documented, the exact pathophysiology of the sympathetic nervous …

Sympathetic neural activity in hypertension and related diseases

G Grassi - American journal of hypertension, 2010 - academic.oup.com
Background Several hemodynamic variables, such as blood pressure, vascular resistance,
cardiac output, and heart rate, are regulated, among others, by sympathetic cardiovascular …

The sympathetic system in hypertension. State-of-the-art review.

FM Abboud - Hypertension, 1982 - Am Heart Assoc
One may postulate a genetic defect in membrane permeability, in the transport of sodium, or
in the sodium pump in vascular muscle which could account for increased intracellular …