Open questions about metabolically normal obesity

Z Pataky, E Bobbioni-Harsch, A Golay - International journal of obesity, 2010 - nature.com
Subsets of obese subjects without any cardiometabolic risk factors have been repeatedly
described. This raises questions whether obesity 'per se'enhances the risk for …

Metabolic normality in overweight and obese subjects. Which parameters? Which risks?

Z Pataky, V Makoundou, P Nilsson… - International journal of …, 2011 - nature.com
Objectives: The objective of this study was to define metabolic normality and to investigate
the cardiometabolic profile of metabolically normal obese. Design: Cross-sectional study …

To be obese—does it matter if you are metabolically healthy?

AD Karelis - Nature Reviews Endocrinology, 2011 - nature.com
Health-care professionals must be educated about the existence of obese individuals who
are metabolically healthy and normal-weight individuals who are metabolically unhealthy. A …

Are there persons who are obese, but metabolically healthy?

EAH Sims - Metabolism-Clinical and Experimental, 2001 - metabolismjournal.com
The aim of this article was to review the evidence for a metabolically normal subset of the
obese and its implications for clinical and research work. The methods included literature …

Metabolic and body composition factors in subgroups of obesity: what do we know?

AD Karelis, DH St-Pierre, F Conus… - The Journal of …, 2004 - academic.oup.com
Obesity is thought to be a heterogeneous disorder with several possible etiologies;
therefore, by examining subtypes of obesity we attempt to understand obesity's …

Normal-weight obesity: implications for cardiovascular health

N Jean, VK Somers, O Sochor… - Current atherosclerosis …, 2014 - Springer
We sought to review the epidemiological features and clinical implications of normal-weight
obesity. The concept of normal-weight obesity has been recently reported as an important …

Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality--a systematic …

LL Roberson, EC Aneni, W Maziak, A Agatston… - BMC public health, 2014 - Springer
Background A subgroup has emerged within the obese that do not display the typical
metabolic disorders associated with obesity and are hypothesized to have lower risk of …

Healthy obese versus unhealthy lean: the obesity paradox

CJ Lavie, A De Schutter, RV Milani - Nature Reviews Endocrinology, 2015 - nature.com
Overweight and obesity have reached epidemic proportions in the USA and most of the rest
of the world. Particularly concerning is the very high prevalence of class III obesity (BMI≥ 40 …

Metabolically healthy obesity: definitions, determinants and clinical implications

CM Phillips - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …

Metabolic health in normal-weight and obese individuals

MB Schulze - Diabetologia, 2019 - Springer
Cardiovascular complications are commonly associated with obesity. However, a subgroup
of obese individuals may not be at an increased risk for cardiovascular complications; these …