[PDF][PDF] Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene

F Cao, T Jin, Y Zhou - Biomedical and Environmental Sciences, 2006 - besjournal.com
Objective To explore the mechanisms by which genistein and daidzein inhibit the growth of
prostate cancer cells. Methods LNCaP and PC-3 cells were exposed to genistein and …

Effects of soybean isoflavones on cell growth and apoptosis of the human prostatic cancer cell line LNCaP

M Onozawa, K Fukuda, M Ohtani… - Japanese journal of …, 1998 - academic.oup.com
Background: Epidemiological studies have suggested that soybean isoflavones are
associated with a lower risk of prostate cancer. However, the mechanisms of prostate cancer …

Combination of low dose of genistein and daidzein has synergistic preventive effects on isogenic human prostate cancer cells when compared with individual soy …

X Dong, W Xu, RA Sikes, C Wu - Food chemistry, 2013 - Elsevier
The reduced incidence of prostate cancer (PCa) in Asia countries has been attributed to
high soy diets, and major soy isoflavones, in particular daidzein and genistein, are thought …

Genistein and daidzein: different molecular effects on prostate cancer

M Adjakly, M Ngollo, JP Boiteux, YJ Bignon… - Anticancer …, 2013 - ar.iiarjournals.org
Diet is believed to play an important role in cancer. It has been revealed by epidemiological
studies that Asian populations, who consume phytoestrogens in large amounts, have a …

Molecular basis of the anti-cancer effects of genistein isoflavone in LNCaP prostate cancer cells

K Merchant, J Kumi-Diaka, A Rathinavelu… - Functional Foods in …, 2011 - ffhdj.com
Background: Prostate cancer is the most common form of non-skin cancer within the United
States and the second leading cause of cancer deaths. Survival rates for the advanced …

[HTML][HTML] Evaluation of anticancer and cytotoxic effects of genistein on PC3 prostate cell line under three-dimensional culture medium

SM Khamesi, MS Barough, J Zargan… - Iranian biomedical …, 2022 - ncbi.nlm.nih.gov
Background: Prostate cancer is a major cause of disease and mortality among men. GNT is
an isoflavone found naturally in legumes. Isoflavones, a subset of phytoestrogens, are …

Genistein and daidzein act on a panel of genes implicated in cell cycle and angiogenesis by polymerase chain reaction arrays in human prostate cancer cell lines

N Rabiau, M Kossaï, M Braud, N Chalabi, S Satih… - Cancer …, 2010 - Elsevier
Background: The prostate cancer most frequently affects men. The ethnic origin and family
antecedents of prostate cancer are established as risk factors. The genetic factors …

Involvement of the Estrogen Receptor β in Genistein-induced Expression of p21waf1/cip1 in PC-3 Prostate Cancer Cells

K Matsumura, T Tanaka, H Kawashima… - Anticancer …, 2008 - ar.iiarjournals.org
Background: Dietary genistein, a phytoestrogen derived from soybean, has been suggested
as a chemopreventive agent for prostate cancer. Genistein has been reported to exert its …

Daidzein Effect on Hormone Refractory Prostate Cancer In Vitro and In Vivo Compared to Genistein and Soy Extract: Potentiation of Radiotherapy

V Singh-Gupta, H Zhang, CK Yunker, Z Ahmad… - Pharmaceutical …, 2010 - Springer
Purpose Genistein, the major bioactive isoflavone of soybeans, acts as a radiosensitizer for
prostate cancer (PCa) both in vitro and in vivo. However, pure genistein promoted increased …

Pharmacological potential of phytoestrogens in the treatment of prostate cancer

P Thelen, F Seseke, RH Ringert, W Wuttke… - Der Urologe, 2006 - Springer
Introduction Phytoestrogenes are plant-derived compounds that have been shown to exert
an antiproliferative potential on prostate cancer cells, although the exact mechanisms are …