Translational Therapeutic Str ategies in Amyotrophic Lateral Sclerosis
H Ryu, RJ Ferrante - Mini Reviews in Medicinal Chemistry, 2007 - ingentaconnect.com
Amyotrophic lateral sclerosis (ALS) is a clinically severe and fatal neurodegenerative
disease characterized by a loss of both upper and lower motor neurons, resulting in …
disease characterized by a loss of both upper and lower motor neurons, resulting in …
Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …
Prospects for the pharmacotherapy of amyotrophic lateral sclerosis: old strategies and new paradigms for the third millennium
BW Festoff, Z Suo, BA Citron - CNS drugs, 2003 - Springer
Biomedical researchers interested in amyotrophic lateral sclerosis (ALS) must invoke newly
developing technologies if we are to discover pharmaceutical treatments that will help a …
developing technologies if we are to discover pharmaceutical treatments that will help a …
Amyotrophic lateral sclerosis: current therapeutic perspectives
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …
Recent advances in amyotrophic lateral sclerosis research: perspectives for personalized clinical application
Abstract Treatment of amyotrophic lateral sclerosis (ALS) has been fueled, in part, by
frustration over the shortcomings of the symptomatic drugs available, since these do not …
frustration over the shortcomings of the symptomatic drugs available, since these do not …
Roots to start research in amyotrophic lateral sclerosis: molecular pathways and novel therapeutics for future
D Harikrishnareddy, S Misra, S Upadhyay… - Reviews in the …, 2015 - degruyter.com
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
Biomarkers and future targets for development in amyotrophic lateral sclerosis
Although the pathophysiological mechanisms underlying the development of amyotrophic
lateral sclerosis (ALS) remain to be fully elucidated, there have been significant advances in …
lateral sclerosis (ALS) remain to be fully elucidated, there have been significant advances in …
New therapeutic targets for amyotrophic lateral sclerosis
M Kuzma-Kozakiewicz, H Kwiecinski - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
Therapeutic development in amyotrophic lateral sclerosis
M Bucchia, A Ramirez, V Parente, C Simone… - Clinical …, 2015 - Elsevier
Purpose Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …