Africa is experiencing a rapid increase in adult obesity and associated cardiometabolic
diseases (CMDs). The H3Africa AWI-Gen Collaborative Centre was established to examine …

There is an alarming tide of cardiovascular and metabolic disease (CMD) sweeping across
Africa. This may be a result of an increasingly urbanized lifestyle characterized by the …

Cardiovascular diseases, principally ischaemic heart disease and stroke, are the leading
causes of global mortality and morbidity. Together with other non-communicable diseases …

Advance Access Publication Date: 13 October 2020 Cohort Profile from middle-to old-age.
This will further the aetiological understanding of heart failure, exercise intolerance and …

A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …

Substantial advances have been made in identifying common genetic variants influencing
cardiometabolic traits and disease outcomes through genome wide association studies …

Background: African populations are characterised by diversity at many levels including:
demographic history, genetic ancestry, language, wealth, socio-political landscape, culture …

Background Obesity is a major risk factor for emerging non-communicable diseases (NCDS)
in middle income countries including South Africa (SA). Understanding the multiple and …

The genomic architecture of African populations is poorly understood and there is
considerable variation between ethno-linguistic groups. Genome-wide approaches have …

Background There is a dearth of information on diet-related chronic diseases in West Africa.
This cross-sectional study assessed the rate of obesity and other cardiovascular disease …