Background VEGF proteolysis by plasmin or matrix metalloproteinases (MMPs) is believed
to play an important role in regulating vascular patterning in vivo by releasing VEGF from the …

Background The spatial distribution of vascular endothelial growth factor A (VEGF) is an
important mediator of vascular patterning. Previous experimental studies in the mouse …

Vascular endothelial growth factor (VEGF) signal transduction through the cell surface
receptors VEGFR1 and VEGFR2 regulates angiogenesis—the growth of new capillaries …

Matrix-binding isoforms and non-matrix-binding isoforms of vascular endothelial growth
factor (VEGF) are both capable of stimulating vascular remodeling, but the resulting blood …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Vascular endothelial growth factor (VEGF) is a critical mediator of blood vessel formation
during development and in pathological conditions. In this study, we demonstrate that VEGF …

Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor
1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To …

Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific
receptors on the endothelial cells lining blood vessels. The signaling cascade triggered …

The splice isoforms of vascular endothelial growth A (VEGF) each have different affinities for
the extracellular matrix (ECM) and the coreceptor NRP1, which leads to distinct vascular …

The extracellular matrix plays a critical role in orchestrating the events necessary for wound
healing, muscle repair, morphogenesis, new blood vessel growth, and cancer invasion. In …