VEGF‐A (VEGF) drives angiogenesis through activation of downstream effectors to promote
endothelial cell proliferation and migration. Although VEGF binds both VEGF receptor 1 (R1) …

The vascular endothelial growth factor (VEGF) family of cytokines is involved in the
maintenance of existing adult blood vessels as well as in angiogenesis, the sprouting of new …

Angiogenesis is a complex morphogenetic process whereby endothelial cells from existing
vessels invade as multicellular sprouts to form new vessels. Here, we have engineered a …

Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis, the growth of
new capillaries from existing microvasculature. In peripheral arterial disease (PAD), lower …

We built a whole‐body computational model to study the role of the poorly understood
vascular endothelial growth factor (VEGF) 165b splice isoform in peripheral artery disease …

Computational modeling of angiogenesis is limited by a lack of experimental data on
angiogenic receptor levels. Recent receptor profiling quantified vascular endothelial growth …

Signal transduction by vascular endothelial growth factors (VEGFs) through their cognate
VEGF receptor tyrosine kinases follows the consensus scheme for receptor tyrosine kinases …

During vessel sprouting, endothelial cells (ECs) dynamically rearrange positions in the
sprout to compete for the tip position. We recently identified a key role for the glycolytic …

Plasmin-catalyzed cleavage of the vascular endothelial growth factor (VEGF)-A isoform
VEGF165 results in loss of its carboxyl-terminal heparin-binding domain and significant loss …

VEGFs (vascular endothelial growth factors) are a family of conserved disulfide-linked
soluble secretory glycoproteins found in higher eukaryotes. VEGFs mediate a wide range of …