Blood vessel expansion is driven by sprouting angiogenesis of endothelial cells, and is
essential for development, wound healing and disease. Membrane-localized vascular …

Angiogenesis is the growth of new blood vessels from pre-existing microvessels. Peripheral
arterial disease (PAD) is caused by atherosclerosis that results in ischemia mostly in the …

Vascular endothelial growth factor (VEGF) spatial and temporal activity must be tightly
controlled during angiogenesis to form perfusable vasculature in a healing wound. The …

Abstract Vascular Endothelial Growth Factor (VEGF) signal transduction is central to
angiogenesis in development and in pathological conditions such as cancer, retinopathy …

Angiogenesis is a complex, multicellular process that involves bidirectional interactions
between extracellular matrix (ECM) and collectively invading endothelial cell (EC) sprouts …

Proteolysis of fibrin matrices by endothelial cells plays essential roles in the migratory and
morphogenic differentiation processes underlying angiogenesis. Using an in vitro …

Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis that
stimulates proliferation, migration, and proteolytic activity of endothelial cells. Although the …

Vascular endothelial growth factor (VEGF) signal transduction is central to angiogenesis in
development and in pathological conditions such as cancer, retinopathy and ischemic …

Simple Summary Vascular endothelial growth factors (VEGFs) regulate the growth of blood
and lymphatic vessels. Some of them induce the growth of blood vessels, and others the …

Aims Vascular endothelial growth factor (VEGF)-initiated angiogenesis requires coordinated
proteolytic degradation of extracellular matrix provided by the urokinase plasminogen …