Nationwide efficacy-safety study of nebivolol in mildly hypertensive patients

TJ Cleophas, R Agrawal, A Lichtenthal… - American journal of …, 2006 - journals.lww.com
Nebivolol has been adequately tested in clinical efficacy trials of patients with mild
hypertension. Clinical efficacy trials or their metaanalyses did not accurately predict the …

A Randomized, Double‐Blind, Placebo‐Controlled Parallel‐Group Study to Assess the Efficacy and Safety of Nebivolol, a Novel β‐Blocker, in Patients With Mild to …

RJ Weiss, MA Weber, AA Carr… - The Journal of Clinical …, 2007 - Wiley Online Library
This double‐blind, multicenter, randomized placebo‐controlled study evaluated the
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …

Long-term efficacy of nebivolol monotherapy in patients with hypertension

TJ Cleophas, I Grabowsky, MG Niemeyer… - Current therapeutic …, 2001 - Elsevier
Background: The antihypertensive activity of beta-blockers generally increases during the
first 6 to 8 weeks of treatment; however, no study has systematically assessed whether blood …

[引用][C] Nebivolol in Hypertension: One-Year Treatment Data

G Sieben, L Van Nueten, J Symoens - Drug Investigation, 1991 - Springer
In order to evaluate the efficacy and tolerability of nebivolol during long term treatment of
outpatients with hypertension, 6 open multicentre studies are being carried out in 5 different …

Comparison of Nebivolol monotherapy versus Nebivolol in combination with other antihypertensive therapies for the treatment of hypertension

V Papademetriou - The American journal of cardiology, 2009 - Elsevier
Nebivolol is a novel, β1-adrenergic receptor blocker with vasodilatory properties mediated
through the activation of the l-arginine/nitric oxide pathway. Short-term randomized clinical …

Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis

LM Van Bortel, F Fici, F Mascagni - American Journal of Cardiovascular …, 2008 - Springer
Background and objective Lowering BP to normal levels without quality of life deterioration
is the most important means of reducing cardiovascular risk. Recent studies have …

The efficacy and tolerability of nebivolol in hypertensive African American patients

E Saunders, WB Smith, KB DeSalvo… - The Journal of …, 2007 - Wiley Online Library
Hypertensive African Americans often respond poorly to β‐blocker monotherapy, compared
with whites. There is evidence, however, that suggests that this response may be different if …

A critical review of nebivolol and its fixed-dose combinations in the treatment of hypertension

AFG Cicero, M Kuwabara, C Borghi - Drugs, 2018 - Springer
Abstract β-Adrenergic receptor blockers (β-blockers) are well-known useful and cost-
effective drugs for managing hypertensive patients with coronary heart disease, stroke, and …

P-251: Nebivolol in the treatment of patients with stage 1 and stage 2 hypertension: Results of a randomized, double-blind, placebo-controlled study

RJ Weiss, MA Weber, AA Carr… - American Journal of …, 2005 - search.proquest.com
The purpose of this study was to establish the antihypertensive efficacy and safety of
nebivolol-a novel, highly selective β 1 blocker with nitric-oxide mediated vasodilatory effects …

Nebivolol: A third-generation β-blocker for hypertension

JWM Cheng - Clinical therapeutics, 2009 - Elsevier
Background: Nebivolol is a third-generation β1-selective β-blocker that is approved for the
treatment of hypertension. Objective: This article reviews the clinical pharmacology of …