The role of interleukin-10 in critical illness
SM Opal, CE Huber - Current Opinion in Infectious Diseases, 2000 - journals.lww.com
Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple
actions affecting the innate immune system as well as humoral and cellular immune …
actions affecting the innate immune system as well as humoral and cellular immune …
The therapeutic potential of interleukin 10 in infection and inflammation
A Kumar, WD Creery - Inflammation, 2001 - Springer
Abstract Interleukin 10 (IL-10), a cytokine with inhibitory activity on inflammation and cell-
mediated immune responses, holds enormous potential for the treatment of inflammatory …
mediated immune responses, holds enormous potential for the treatment of inflammatory …
Interleukin-10: potential benefits and possible risks in clinical infectious diseases
SM Opal, JC Wherry, P Grint - Clinical infectious diseases, 1998 - academic.oup.com
Abstract Human interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that inhibits the
synthesis of the major proinflammatory cytokines and chemokines. IL-10 is the principal TH2 …
synthesis of the major proinflammatory cytokines and chemokines. IL-10 is the principal TH2 …
Interleukin-10: a complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug
A Oberholzer, C Oberholzer, LL Moldawer - Critical care medicine, 2002 - journals.lww.com
Abstract Interleukin (IL)-10 is a pleiotropic cytokine produced by both T cells and
macrophages and possesses both anti-inflammatory and immunosuppressive properties. IL …
macrophages and possesses both anti-inflammatory and immunosuppressive properties. IL …
Interleukin-10: cytokines in anti-inflammation and tolerance
A Howes, P Stimpson, P Redford, L Gabrysova… - … Frontiers: Regulation of …, 2014 - Springer
Abstract Interleukin (IL)-10 is an immunosuppressive cytokine produced by many cells of the
innate and adaptive immune response, including macrophages, dendritic cells, B cells, and …
innate and adaptive immune response, including macrophages, dendritic cells, B cells, and …
IL-10: the master regulator of immunity to infection
KN Couper, DG Blount, EM Riley - The Journal of Immunology, 2008 - journals.aai.org
IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …
cells, and macrophages, all of which are required for optimal pathogen clearance but also …
[HTML][HTML] The role of interleukin-10 in the pathogenesis of bacterial infection
T Van Der Poll, A Marchant… - Clinical Microbiology and …, 1997 - Elsevier
Infection is associated with enhanced production of cytokines, low-molecular-weight
proteins important for the orchestration of inflammatory processes. Research on the role of …
proteins important for the orchestration of inflammatory processes. Research on the role of …
Recent insights into microbial triggers of interleukin-10 production in the host and the impact on infectious disease pathogenesis
Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …
Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens
JC Cyktor, J Turner - Infection and immunity, 2011 - Am Soc Microbiol
The generation of an effective immune response against an infection while also limiting
tissue damage requires a delicate balance between pro-and anti-inflammatory responses …
tissue damage requires a delicate balance between pro-and anti-inflammatory responses …
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …