Objective Gore‐tex bags were placed over sheep ovaries and tissue reaction was assessed.
Setting The study was conducted at The University of Queensland under the supervision of …

Systems to assess the toxicity of materials used in human assisted reproduction currently
lack efficiency and/or sufficient discriminatory power. The development of 1-cell CBA/B6 F1 …

Reproductive toxicity refers to the adverse effects of a substance on any aspect of the
reproductive cycle. There are different conventional animal tests for assessing reproductive …

Since the latter part of the twentieth century in this country, there has been an increase in the
number of working women and a tendency for women to postpone the start of a family …

Mammalian embryo represents a dynamic biological system undergoing constant changes
through cell divisions, cell migrations and cell differentiations It is therefore obvious that the …

There are several routes of exposure to gonadotoxins for the male. Exposures originate from
lifestyle choices, medications, and treatment for malignancies, as well as occupational and …

Experience with drugs and other xenobiotics indicates that both animal testing and
epidemiological studies are necessary to provide adequate data for an estimation of risks …

The dramatic increase in the number of animals required for reproductive toxicity testing
imposes the validation of alternative methods to reduce the use of laboratory animals. As we …

Women presenting fertility problems are often helped by Assisted Reproductive Techniques
(ART), such as in vitro fertilization (IVF) programs. However, in many cases the etiology of …

To date, approximately 60 chemicals have been identified as endocrine disruptors:
exogenous agents that interfere with various aspects of natural hormone physiology. The …