Background It remains unclear whether persistent loneliness is related to brain structures
that are associated with cognitive decline and development of Alzheimer's disease (AD) …

Background and Objectives Loneliness is common, and its prevalence is rising. The
relationship of loneliness with subsequent dementia and the early preclinical course of …

Background Loneliness is most prevalent during adolescence and late life and has been
associated with mental health disorders as well as with cognitive decline during aging …

Objectives Loneliness has been shown to increase the risk of dementia. However, it is
unclear why greater loneliness is associated with greater susceptibility to dementia. Herein …

Background: Loneliness has been highlighted as a risk factor for dementia. However, the
nature of the relationship between loneliness and cognitive function prior to onset of …

Background Loneliness precedes the onset of cognitive impairment (CI) in older adults.
Although the mechanisms through which loneliness “gets under the skin” to influence the …

Loneliness significantly contributes to cognitive impairment and dementia in older adults.
Loneliness is a distressing feeling resulting from a perceived lack of social connection (ie, a …

Ample evidence indicates that loneliness in old age is associated with poor bodily and
mental health. However, little is known about structural cerebral correlates of loneliness in …

In aging populations, increasing amounts of older adults are reporting high levels of
loneliness. Previous research has demonstrated that people reporting more loneliness have …

Objectives: To examine the relationship between loneliness and cognitive function and to
explore the mediating role of physical health on the loneliness–cognition relationship in …