Identification of SLC25A37 as a major depressive disorder risk gene

YX Huo, L Huang, DF Zhang, YG Yao, YR Fang… - Journal of psychiatric …, 2016 - Elsevier
Major depressive disorder (MDD) is one of the most prevalent and disabling mental
disorders, but the genetic etiology remains largely unknown. We performed a meta-analysis …

Resequencing three candidate genes for major depressive disorder in a Dutch cohort

EC Verbeek, MR Bevova, Z Bochdanovits, P Rizzu… - PLoS …, 2013 - journals.plos.org
Major depressive disorder (MDD) is a psychiatric disorder, characterized by periods of low
mood of more than two weeks, loss of interest in normally enjoyable activities and …

New evidence for the association of the serotonin transporter gene (SLC6A4) haplotypes, threatening life events, and depressive phenotype

J Lazary, A Lazary, X Gonda, A Benko, E Molnar… - Biological …, 2008 - Elsevier
BACKGROUND: Since the first report of the significant gene-environment interaction (G× E)
in depression published by Caspi et al., the literature is considerably contradictory in this …

Regulatory mechanisms of major depressive disorder risk variants

S Li, Y Li, X Li, J Liu, Y Huo, J Wang, Z Liu, M Li… - Molecular …, 2020 - nature.com
Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders and a
leading cause of disability worldwide. Though recent genome-wide association studies …

Overlapping common genetic architecture between major depressive disorders and anxiety and stress-related disorders

L Mei, Y Gao, M Chen, X Zhang, W Yue… - Progress in Neuro …, 2022 - Elsevier
Major depressive disorders (MDDs) and anxiety and stress-related disorders (ASRDs) have
overlapping symptoms and high rates of comorbidity. However, the underlying mechanisms …

Common variants on 6q16. 2, 12q24. 31 and 16p13. 3 are associated with major depressive disorder

X Li, Z Luo, C Gu, LS Hall, AM McIntosh… - …, 2018 - nature.com
Accumulating evidence suggests that genetic factors have a role in major depressive
disorder (MDD). However, only limited MDD risk loci have been identified so far. Here we …

Poor replication of candidate genes for major depressive disorder using genome-wide association data

FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide
association study (GWAS) in major depressive disorder (MDD) were used to explore …

Rare variants in SLC6A4 cause susceptibility to major depressive disorder with suicidal ideation in Han Chinese adolescents and young adults

L Ran, M Ai, W Wang, J Chen, T Wu, W Liu, J Jin… - Gene, 2020 - Elsevier
Background Suicidal ideation (SI) is the most serious symptom of major depressive disorder
(MDD) and considered an extreme state. The serotonin transporter gene (SLC6A4) plays a …

Meta-analyses of genetic studies on major depressive disorder

S López-León, A Janssens… - Molecular …, 2008 - nature.com
The genetic basis of major depressive disorder (MDD) has been investigated extensively,
but the identification of MDD genes has been hampered by conflicting results from …

Genome-wide association studies on Northern Italy isolated populations provide further support concerning genetic susceptibility for major depressive disorder

V Dattilo, S Ulivi, A Minelli, M La Bianca… - The World Journal of …, 2023 - Taylor & Francis
Objectives Major depressive disorder (MDD) is a psychiatric disorder with pathogenesis
influenced by both genetic and environmental factors. To date, the molecular-level …