The dynamic roles of intracellular lipid droplets: from archaea to mammals
DJ Murphy - Protoplasma, 2012 - Springer
During the past decade, there has been a paradigm shift in our understanding of the roles of
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …
[HTML][HTML] Lipid droplet proteins and metabolic diseases
Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …
Lipid droplets in health and disease
Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …
Lipid droplets and cellular lipid metabolism
TC Walther, RV Farese Jr - Annual review of biochemistry, 2012 - annualreviews.org
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
Lipid droplet dynamics in budding yeast
CW Wang - Cellular and molecular life sciences, 2015 - Springer
Eukaryotic cells store excess fatty acids as neutral lipids, predominantly triacylglycerols and
sterol esters, in organelles termed lipid droplets (LDs) that bulge out from the endoplasmic …
sterol esters, in organelles termed lipid droplets (LDs) that bulge out from the endoplasmic …
[HTML][HTML] Lipid droplets: a dynamic organelle moves into focus
Lipid droplets (LDs) were perceived as static storage deposits, which passively participate in
the energy homeostasis of both cells and entire organisms. However, this view has changed …
the energy homeostasis of both cells and entire organisms. However, this view has changed …
Mechanisms of lipid droplet biogenesis
Lipid droplets (LDs) are organelles that compartmentalize nonbilayer-forming lipids in the
aqueous cytoplasm of cells. They are ubiquitous in most organisms, including in animals …
aqueous cytoplasm of cells. They are ubiquitous in most organisms, including in animals …
Not just fat: the structure and function of the lipid droplet
T Fujimoto, RG Parton - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
Cytosolic lipid droplets: from mechanisms of fat storage to disease
The lipid droplet (LD) is a phylogenetically conserved organelle. In eukaryotes, it is born
from the endoplasmic reticulum, but unlike its parent organelle, LDs are the only known …
from the endoplasmic reticulum, but unlike its parent organelle, LDs are the only known …
Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites
Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …