Background Alzheimer's disease (AD) is the most common neurodegenerative disorder.
Depositions of amyloid β peptide (Aβ) and tau protein are among the major pathological …

Background Alzheimer's disease (AD) is the most common type of dementia affecting people
over 65 years of age. The hallmarks of AD are the extracellular deposits known as amyloid β …

Background: Alzheimer's disease (AD) is the most prevalent form of dementia with two
pathological hallmarks of tau-containing neurofibrillary tangles and amyloid-β protein (Aβ) …

Alzheimer's disease (AD) is a progressive brain amyloidosis that injures brain regions
involved in memory consolidation and other higher brain functions. Neuropathologically, the …

Background Alzheimer's disease (AD) is a progressive, chronic, and neurodegenerative
disease, and the most common cause of dementia worldwide. Currently, the mechanisms …

Background Based on amyloid cascade and tau hypotheses, protein biomarkers of different
Aβ and tau species in cerebrospinal fluid (CSF) and blood/plasma/serum have been …

Background Altered proteome profiles have been reported in both postmortem brain tissues
and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with …

Neuropathological studies have shown that the typical neurofibrillary pathology of
hyperphosphorylated tau protein in Alzheimer's disease (AD) preferentially affects specific …

The brain represents one of the most divergent and critical organs in the human body. Yet, it
can be afflicted by a variety of neurodegenerative diseases specifically linked to aging …

Objective We aimed to test whether region‐specific factors, including spatial expression
patterns of the tau‐encoding gene MAPT and regional levels of amyloid positron emission …