We show that connexin expression and in vivo patterns of communication were dramatically
altered in response to epidermal wounding. Six hours after injury, Cx26 was up-regulated in …

Wound healing is a complex process requiring communication for the precise co‐ordination
of different cell types. The role of extracellular communication through growth factors in the …

To analyze the effect of connexin loss on the repair of wounded tail skin, we have studied
the following transgenic mouse mutants: connexin30–/–, connexin31–/–and connexin43 Cre …

Wounding of endothelial cells is associated with altered direct intercellular communication.
To determine whether gap junctional communication participates to the wound repair …

Gap junctions (GJ) are known to be involved in spontaneous wound healing in rodent skin.
We analyzed the staining patterns of the GJ proteins Cx26, Cx30, and Cx43 in human …

We examined changes in the expression and localization of connexin proteins and
transcripts by means of immunofluorescence and in situ hybridization in normal conditions …

Background Regulated alteration of connexin expression has been shown to be integral to
acute wound repair. Downregulation of the gap‐junction protein connexin 43 at the wound …

Phosphorylation of connexin43 (Cx43) on serine368 (S368) has been shown to decrease
gap junctional communication via a reduction in unitary channel conductance. Examination …

Eight different connexins are expressed in mouse epidermis with overlapping expression
patterns in different epidermal layers. Analyses of mice with deficiency or modifications of …

To elucidate mechanisms underlying gap junction‐mediated intercellular communication in
epidermal keratinocytes, we have examined the expression of four connexin genes, Cx26 …