Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma

TJ Musholt, PB Musholt, N Khaladj, D Schulz… - Surgery, 2000 - Elsevier
Background. The expression of RET/PTC chimeras was demonstrated in 10% to 20% of
sporadic papillary thyroid carcinomas (PTCs), whereas rearrangements ofNTRK 1 were …

RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

I Bongarzone, P Vigneri, L Mariani, P Collini… - Clinical cancer research …, 1998 - AACR
The papillary carcinoma family (PCF) of thyroid tumors includes a wide variety of neoplastic
entities regarded as well-differentiated, poorly differentiated, and undifferentiated papillary …

Molecular analysis of the RET and NTRK1 gene rearrangements in papillary thyroid carcinoma in the Polish population

E Brzeziańska, M Karbownik, M Migdalska-Sęk… - Mutation Research …, 2006 - Elsevier
Among different genetic factors involved in the pathogenesis of the papillary thyroid
carcinoma (PTC), rearrangements of RET protooncogene (RET/PTC), as well as …

Ret/PTC activation does not influence clinical and pathological features of adult papillary thyroid carcinomas

E Puxeddu, S Moretti, A Giannico… - European journal of …, 2003 - academic.oup.com
Objective RET proto-oncogene rearrangements (ret/PTCs) represent the most common
genetic alterations found in papillary thyroid carcinomas (PTCs). Correlation of ret/PTC …

Distinct Multiple RET/PTC Gene Rearrangements in Multifocal Papillary Thyroid Neoplasia

SL Sugg, S Ezzat, IB Rosen… - The Journal of Clinical …, 1998 - academic.oup.com
Rearrangements involving the RET protooncogene have been implicated in the
development of papillary thyroid carcinoma (PC). Transgenic mice, expressing thyroid …

RET protein expression has no prognostic impact on the long-term outcome of papillary thyroid carcinoma

F Basolo, E Molinaro, L Agate… - European journal of …, 2001 - academic.oup.com
Background RET proto-oncogene rearrangements (RET/PTC) are causative events in the
pathogenesis of a subset of papillary thyroid cancer (PTC). The prevalence of RET/PTC …

Prevalence of RET/PTC Rearrangements in Thyroid Papillary Carcinomas: Effects of the Detection Methods and Genetic Heterogeneity

Z Zhu, R Ciampi, MN Nikiforova… - The Journal of …, 2006 - academic.oup.com
Context: RET/PTC rearrangements have been reported in papillary thyroid carcinomas with
variable frequency in studies that used different detection methods. Objective: Our objective …

RET/PTC rearrangement in thyroid tumors

YE Nikiforov - Endocrine pathology, 2002 - Springer
Rearrangement of the RET gene, also known as RET/PTC rearrangement, is the most
common genetic alteration identified to date in thyroid papillary carcinomas. The prevalence …

ret/PTC-1,-2, and-3 oncogene rearrangements in human thyroid carcinomas: implications for metastatic potential?

SL Sugg, L Zheng, IB Rosen… - The Journal of …, 1996 - academic.oup.com
The ret/PTC oncogene is unique to papillary thyroid cancer. Three forms of this oncogene,
formed by translocation of three different genes to the tyrosine kinase domain of the ret …

RET/PTC and RET Tyrosine Kinase Expression in Adult Papillary Thyroid Carcinomas

DL Learoyd, M Messina, J Zedenius… - The Journal of …, 1998 - academic.oup.com
The prevalence of RET/PTC rearrangements in papillary thyroid carcinomas (PTCs) varies
widely in different studies, and an association of RET/PTC presence with tumor behavior …