Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and …
Objectives: The goal of this study was to investigate the effect of pre-treatment of
mesenchymal stem cells (MSCs) with growth factors (GFs) on cardiomyogenic …
mesenchymal stem cells (MSCs) with growth factors (GFs) on cardiomyogenic …
Mesenchymal stem cells participate in angiogenesis and improve heart function in rat model of myocardial ischemia with reperfusion
J Tang, Q Xie, G Pan, J Wang… - European Journal of …, 2006 - academic.oup.com
Objective: The effect of transplanted mesenchymal stem cells (MSCs) on the left ventricular
(LV) function and morphology in a rat myocardial infarct heart with reperfusion model were …
(LV) function and morphology in a rat myocardial infarct heart with reperfusion model were …
Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis
N Nagaya, T Fujii, T Iwase, H Ohgushi… - American Journal …, 2004 - journals.physiology.org
Mesenchymal stem cells (MSCs) are pluripotent cells that differentiate into a variety of cells,
including cardiomyocytes and endothelial cells. However, little information is available …
including cardiomyocytes and endothelial cells. However, little information is available …
Mesenchymal stem cells are superior to angiogenic growth factor genes for improving myocardial performance in the mouse model of acute myocardial infarction
KG Shyu, BW Wang, HF Hung, CC Chang… - Journal of Biomedical …, 2006 - Springer
Both cell therapy and angiogenic growth factor gene therapy have been applied to animal
studies and clinical trials. Little is known about the direct comparison between cell therapy …
studies and clinical trials. Little is known about the direct comparison between cell therapy …
Improved function and myocardial repair of infarcted heart by intracoronary injection of mesenchymal stem cell-derived growth factors
BK Nguyen, S Maltais, LP Perrault, JF Tanguay… - Journal of …, 2010 - Springer
Transplantation of mesenchymal stem cells (MSC) improves repair and function recovery
following myocardial infarction (MI), but underlying mechanisms remain to be elucidated. We …
following myocardial infarction (MI), but underlying mechanisms remain to be elucidated. We …
The roles of mesenchymal stem cells (MSCs) therapy in ischemic heart diseases
XJ Wang, QP Li - Biochemical and biophysical research communications, 2007 - Elsevier
Growing cell-based myocardial therapies which could lead to successful myocardial repair
attracts medical interest. Even more intriguing is the observation that MSCs appears to be a …
attracts medical interest. Even more intriguing is the observation that MSCs appears to be a …
Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction
YL Tang, Q Zhao, X Qin, L Shen, L Cheng, J Ge… - The Annals of thoracic …, 2005 - Elsevier
BACKGROUND: There are several reports that engrafted mesenchymal stem cells (MSCs)
stimulate angiogenesis in the ischemic heart, but the mechanism remains controversial. We …
stimulate angiogenesis in the ischemic heart, but the mechanism remains controversial. We …
Mesenchymal stem cell therapy: A promising cell‐based therapy for treatment of myocardial infarction
AES Shafei, MA Ali, HG Ghanem… - The journal of gene …, 2017 - Wiley Online Library
For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …
Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model
Background—Mesenchymal stem cells (MSCs) offer a novel therapeutic option in the
treatment of acute myocardial infarction. MSCs are able to differentiate into myogenic cells …
treatment of acute myocardial infarction. MSCs are able to differentiate into myogenic cells …
Pretreatment of mesenchymal stem cells with angiotensin II enhances paracrine effects, angiogenesis, gap junction formation and therapeutic efficacy for myocardial …
C Liu, Y Fan, HY Zhu, YC Song, L Hu, Y Wang… - International Journal of …, 2015 - Elsevier
Background Pretreatment of mesenchymal stem cells (MSCs) with growth factors is reported
to be an effective route for improving cell-based therapy of myocardial infarction (MI) …
to be an effective route for improving cell-based therapy of myocardial infarction (MI) …
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