The antioxidant and anti-inflammatory effects of flavonoids from propolis via Nrf2 and NF-κB pathways

W Xu, H Lu, Y Yuan, Z Deng, L Zheng, H Li - Foods, 2022 - mdpi.com
Accumulating evidence shows that oxidative stress and inflammation contribute to the
development of cardiovascular disease. It has been suggested that propolis possesses …

Comparisons of ethanol extracts of Chinese propolis (poplar type) and poplar gums based on the antioxidant activities and molecular mechanism

J Zhang, X Cao, S Ping, K Wang, J Shi… - Evidence‐Based …, 2015 - Wiley Online Library
The biological activities of propolis are varied from plant sources and the prominent
antioxidant effects of Chinese propolis (poplar type) have been extensively reported …

Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages

MC Búfalo, I Ferreira, G Costa, V Francisco… - Journal of …, 2013 - Elsevier
Ethnopharmacological relevance Propolis is a bee product with numerous biological and
pharmacological properties, such as immunomodulatory and anti-inflammatory activities. It …

Brazilian green propolis inhibits ox‐LDL‐stimulated oxidative stress in human umbilical vein endothelial cells partly through PI3K/Akt/mTOR‐mediated Nrf2/HO‐1 …

W Yuan, H Chang, X Liu, S Wang… - Evidence‐Based …, 2019 - Wiley Online Library
Propolis has been widely used as a dietary supplement for its health benefits, including
cardiovascular protective effects. The aim of this study was to investigate the cytoprotective …

[HTML][HTML] Polyphenol-rich propolis extracts from China and Brazil exert anti-inflammatory effects by modulating ubiquitination of TRAF6 during the activation of NF-κB

K Wang, L Hu, XL Jin, QX Ma, MC Marcucci… - Journal of Functional …, 2015 - Elsevier
Propolis has documented anti-inflammatory properties, although its mechanisms of action
are poorly understood. In this study, the anti-inflammatory effects of polyphenol-rich propolis …

Propolis protects endotoxin induced acute lung and liver inflammation through attenuating inflammatory responses and oxidative stress

B Yangi, M Cengiz Ustuner, M Dincer… - Journal of medicinal …, 2018 - liebertpub.com
Propolis is a natural bee product, and it has many effects, including antioxidant, anti-
inflammatory, antihepatotoxic, and anticancer activity. In this study, we aimed to explore the …

Bioactive components and mechanisms of Chinese poplar propolis alleviates oxidized low-density lipoprotein-induced endothelial cells injury

H Chang, W Yuan, H Wu, X Yin, H Xuan - BMC complementary and …, 2018 - Springer
Background Propolis, a polyphenol-rich natural product, has been used as a functional food
in anti-inflammation. However, its bioactive components and mechanisms have not been …

Brazilian red propolis extract enhances expression of antioxidant enzyme genes in vitro and in vivo

S Hotta, S Uchiyama, K Ichihara - Bioscience, Biotechnology …, 2020 - academic.oup.com
Brazilian red propolis reportedly has reactive oxygen species (ROS) scavenging effects in
vitro, but the cellular mechanisms remain unclear. In the present study, the effects of an …

Propolis attenuates lipopolysaccharide‐induced inflammatory responses through intracellular ROS and NO levels along with downregulation of IL‐1β and IL‐6 …

F Asgharpour, AA Moghadamnia… - Journal of food …, 2019 - Wiley Online Library
Propolis had a wide spectrum of biological activities. In the current study, antioxidative and
the immunomodulatory effects of the Polur ethanol extract of propolis (PEEP) in murine …

Molecular Mechanisms Underlying the In Vitro Anti‐Inflammatory Effects of a Flavonoid‐Rich Ethanol Extract from Chinese Propolis (Poplar Type)

K Wang, S Ping, S Huang, L Hu, H Xuan… - Evidence‐Based …, 2013 - Wiley Online Library
China produces the greatest amount of propolis but there is still lack of basic studies on its
pharmacological mechanisms. Our previous study found that ethanol extract from Chinese …