As is the case in most medical subspecialties, the developments in basic and clinical
research of addictive disorders continues to change the field. Research over the past 10 to …

The inhalation of tobacco smoke is the fastest and most efficient-way yet discovered to
deliver nicotine to the brain, but until recent years remarkably little was known about the …

Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …

Heading Abstract Rationale. Recent preclinical behavioral and neurobiological research
has characterized important behavioral features and has identified neurobiological …

This study examined the roles of nicotine dependence and duration of smoking deprivation
as mediators of smoking cue reactivity in 117 individuals enrolled in treatment. Participants …

Smoking‐related cues elicit craving and mesocorticolimbic brain activation in smokers.
Severity of nicotine dependence seems to moderate cue reactivity, but the direction and …

Nicotine induces craving, but the degree of craving is believed to be milder than that with
other abused drugs. In this article, the neurobiological mechanisms of craving for nicotine …

Current understanding of the mechanisms through which nicotine acts to reinforce behavior
is limited. Demonstrated interactions between nicotine and the mesolimbic dopamine …

Nicotine, like other drugs when abused, can produce a wide array of behaviours, some of
which collectively propel 'drug-seeking behaviour'. This review focuses on three stimulus …

In this overview, the present knowledge about the effects of nicotine on neurotransmitter
release in the central nervous system has been evaluated. Five characteristics relating to …