Tumor angiogenesis is a complicated process based upon a sequence of interactions
between tumor and vessel endothelial cells. Tumor conditioned medium has been widely …

The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …

Gold nanoparticles (AuNPs) have recently emerged as prominent vehicles for many
biomedical applications from sensing to delivery. The relevant literature contains conflicting …

Objective To investigate the effects of nanogold in inhibition of angiogenesis and growth of
liver cancer cells. Methods Nanogold was co-incubated with VEGF165 and VDGF121 …

Sorafenib is a multi-kinase inhibitor that has been highlighted as a tumor suppressor due to
its anti-proliferative and anti-angiogenic properties, whereas the clinical application of …

Cholangiocarcinoma (CCA) is a rare malignancy of the biliary tract with extremely poor
clinical outcomes due to a lack of effective therapies to improve disease management. The …

Highlights•Invasion and metastases are central features of cancer malignancy and constitute
the primary cause of death for> 90% of patients with cancer.•The establishment of effective …

Angiogenesis is a process by which vessels are formed through preexisting ones, and this
plays a key role in the progression of solid tumors. However, tumor vessels are influenced …

Here, we report an intrinsic property of gold nanoparticles (nanogold): they can interact
selectively with heparin-binding glycoproteins and inhibit their activity. Gold nanoparticles …

It is currently recognized that perpetual cross talk among key players in tumor
microenvironment such as cancer cells (CCs), cancer associated fibroblasts (CAFs), and …