Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Peptide design principles for antimicrobial applications

MDT Torres, S Sothiselvam, TK Lu… - Journal of molecular …, 2019 - Elsevier
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …

Antimicrobial peptides: possible anti-infective agents

JL Narayana, JY Chen - Peptides, 2015 - Elsevier
Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats.
The Infectious Diseases Society of America has expressed concern on the decrease of …

[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections

J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

[HTML][HTML] Focal targeting of the bacterial envelope by antimicrobial peptides

R Rashid, M Veleba, KA Kline - Frontiers in cell and developmental …, 2016 - frontiersin.org
Antimicrobial peptides (AMPs) are utilized by both eukaryotic and prokaryotic organisms.
AMPs such as the human beta defensins, human neutrophil peptides, human cathelicidin …

Antimicrobial peptides (AMPs): The quintessential 'offense and defense'molecules are more than antimicrobials

S Patel, N Akhtar - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Antimicrobial peptides (AMPs) are cationic amphiphilic molecules with α-helix or β-sheet
linear motifs and linear or cyclic configurations. For their role in 'defense and offense', they …

[HTML][HTML] Antimicrobial peptides

L Zhang, RL Gallo - Current biology, 2016 - cell.com
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Antimicrobial peptides (AMPs): roles, functions and mechanism of action

R Seyfi, FA Kahaki, T Ebrahimi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

Antimicrobial peptides: versatile biological properties

M Pushpanathan, P Gunasekaran… - International journal of …, 2013 - Wiley Online Library
Antimicrobial peptides are diverse group of biologically active molecules with
multidimensional properties. In recent past, a wide variety of AMPs with diverse structures …

The revitalization of antimicrobial peptides in the resistance era

Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
The antibiotic resistance crisis is becoming incredibly thorny due to the indiscriminate
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …