NETosis and the immune system in COVID-19: mechanisms and potential treatments

C Gillot, J Favresse, F Mullier, T Lecompte… - Frontiers in …, 2021 - frontiersin.org
NETosis is a form of neutrophil death leading to the release of extracellular chromatin and
the assembling of proteins, including antiviral proteins, primed by an initial pathogenic …

NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

FP Veras, MC Pontelli, CM Silva… - Journal of Experimental …, 2020 - rupress.org
Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …

The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19)

A Arcanjo, J Logullo, CCB Menezes… - Scientific reports, 2020 - nature.com
The novel coronavirus SARS-CoV-2 causes COVID-19, a highly pathogenic viral infection
threatening millions. The majority of the individuals infected are asymptomatic or mildly …

[HTML][HTML] How NETosis could drive “Post-COVID-19 syndrome” among survivors

SA Sawadogo, B Dighero-Kemp… - Immunology …, 2020 - ncbi.nlm.nih.gov
The extensive world propagation of SARS-CoV-2 with millions of cases of COVID-19 and its
high severity and mortality rates is an unprecedented situation. Initially focused on the …

COVID‐19 and neutrophils: the relationship between hyperinflammation and neutrophil extracellular traps

L Borges, TC Pithon-Curi, R Curi… - Mediators of …, 2020 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is a virus‐induced respiratory disease that may
progress to acute respiratory distress syndrome (ARDS) and is triggered by …

Patients with COVID-19: in the dark-NETs of neutrophils

M Ackermann, HJ Anders, R Bilyy, GL Bowlin… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

Role of neutrophil extracellular traps in COVID-19 progression: an insight for effective treatment

MA Blanch-Ruiz, R Ortega-Luna, G Gómez-García… - Biomedicines, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has resulted in a
pandemic with over 270 million confirmed cases and 5.3 million deaths worldwide. In some …

On the origin of neutrophil extracellular traps in COVID-19

M Pastorek, M Dúbrava, P Celec - Frontiers in Immunology, 2022 - frontiersin.org
Despite ongoing vaccination COVID-19 is a global healthcare problem because of the lack
of an effective targeted therapy. In severe COVID-19 manifesting as acute respiratory …

Neutrophil extracellular traps and by-products play a key role in COVID-19: pathogenesis, risk factors, and therapy

AR Thierry, B Roch - Journal of clinical medicine, 2020 - mdpi.com
Understanding of the pathogenesis of the coronavirus disease-2019 (COVID-19) remains
incomplete, particularly in respect to the multi-organ dysfunction it may cause. We were the …