Structural MRI findings in long-term cannabis users: what do we know?

V Lorenzetti, DI Lubman, S Whittle… - Substance use & …, 2010 - Taylor & Francis
In animal studies, tetrahydrocannabinol (THC) has been found to affect brain morphology,
particularly within areas rich in cannabinoid receptors (eg, hippocampus, cerebral cortex) …

Cortical surface morphology in long-term cannabis users: A multi-site MRI study

Y Chye, C Suo, V Lorenzetti, A Batalla, J Cousijn… - European …, 2019 - Elsevier
Cannabis exerts its psychoactive effect through cannabinoid receptors that are widely
distributed across the cortical surface of the human brain. It is suggested that cannabis use …

Regional brain abnormalities associated with long-term heavy cannabis use

M Yücel, N Solowij, C Respondek… - Archives of general …, 2008 - jamanetwork.com
Context Cannabis is the most widely used illicit drug in the developed world. Despite this,
there is a paucity of research examining its long-term effect on the human brain. Objective …

Cannabis use is quantitatively associated with nucleus accumbens and amygdala abnormalities in young adult recreational users

JM Gilman, JK Kuster, S Lee, MJ Lee… - Journal of …, 2014 - Soc Neuroscience
Marijuana is the most commonly used illicit drug in the United States, but little is known
about its effects on the human brain, particularly on reward/aversion regions implicated in …

Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings

A Batalla, S Bhattacharyya, M Yuecel, P Fusar-Poli… - PloS one, 2013 - journals.plos.org
Background The growing concern about cannabis use, the most commonly used illicit drug
worldwide, has led to a significant increase in the number of human studies using …

Cannabis, cannabinoids, and brain morphology: a review of the evidence

Y Chye, R Kirkham, V Lorenzetti, E McTavish… - Biological Psychiatry …, 2021 - Elsevier
Cannabis and cannabinoid-based products are increasingly being accepted and
commodified globally. Yet there is currently limited understanding of the effect of the varied …

Is cannabis neurotoxic for the healthy brain? A meta‐analytical review of structural brain alterations in non‐psychotic users

M Rocchetti, A Crescini, S Borgwardt… - Psychiatry and …, 2013 - Wiley Online Library
Aims Despite growing research in the field of cannabis imaging, mostly in those with a
psychotic illness, the possible neurotoxic effects of smoked cannabis on the healthy brain …

The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature

V Lorenzetti, N Solowij, A Fornito… - Current …, 2014 - ingentaconnect.com
Cannabis is the most widely used illicit drug worldwide, though it is unclear whether its
regular use is associated with persistent alterations in brain morphology. This review …

Grey matter alterations associated with cannabis use: results of a VBM study in heavy cannabis users and healthy controls

J Cousijn, RW Wiers, KR Ridderinkhof… - Neuroimage, 2012 - Elsevier
Cannabis abuse is related to impairments in a broad range of cognitive functions. However,
studies on cannabis abuse in relation to brain structure are sparse and results are …

Larger gray matter volume in the basal ganglia of heavy cannabis users detected by voxel-based morphometry and subcortical volumetric analysis

A Moreno-Alcázar, B Gonzalvo… - Frontiers in …, 2018 - frontiersin.org
Background: Structural imaging studies of cannabis users have found evidence of both
cortical and subcortical volume reductions, especially in cannabinoid receptor-rich regions …