Early emergence of Yersinia pestis as a severe respiratory pathogen

DL Zimbler, JA Schroeder, JL Eddy… - Nature …, 2015 - nature.com
Yersinia pestis causes the fatal respiratory disease pneumonic plague. Y. pestis recently
evolved from the gastrointestinal pathogen Y. pseudotuberculosis; however, it is not known …

Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation

PA Price, J Jin, WE Goldman - Proceedings of the National …, 2012 - National Acad Sciences
Disease progression of primary pneumonic plague is biphasic, consisting of a
preinflammatory and a proinflammatory phase. During the long preinflammatory phase …

Yersinia pestis and plague

RW Titball, J Hill, DG Lawton… - Biochemical Society …, 2003 - portlandpress.com
Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially
devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia …

[HTML][HTML] Yersinia pestis and Plague: Some knowns and unknowns

R Yang, S Atkinson, Z Chen, Y Cui, Z Du… - Zoonoses (Burlington …, 2023 - ncbi.nlm.nih.gov
Since its first identification in 1894 during the third pandemic in Hong Kong, there has been
significant progress of understanding the lifestyle of Yersinia pestis, the pathogen that is …

Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis

PSG Chain, E Carniel, FW Larimer… - Proceedings of the …, 2004 - National Acad Sciences
Yersinia pestis, the causative agent of plague, is a highly uniform clone that diverged
recently from the enteric pathogen Yersinia pseudotuberculosis. Despite their close genetic …

Early Host Cell Targets of Yersinia pestis during Primary Pneumonic Plague

RD Pechous, V Sivaraman, PA Price, NM Stasulli… - PLoS …, 2013 - journals.plos.org
Inhalation of Yersinia pestis causes primary pneumonic plague, a highly lethal syndrome
with mortality rates approaching 100%. Pneumonic plague progression is biphasic, with an …

Pneumonic plague: the darker side of Yersinia pestis

RD Pechous, V Sivaraman, NM Stasulli… - Trends in …, 2016 - cell.com
Inhalation of the bacterium Yersinia pestis results in primary pneumonic plague. Pneumonic
plague is the most severe manifestation of plague, with mortality rates approaching 100% in …

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

CE Demeure, O Dussurget, G Mas Fiol… - Genes & …, 2019 - nature.com
Plague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from
rodent reservoirs, Y. pestis emerged< 6000 years ago from an enteric bacterial ancestor …

Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity

WW Lathem, SD Crosby, VL Miller… - Proceedings of the …, 2005 - National Acad Sciences
Although pneumonic plague is the deadliest manifestation of disease caused by the
bacterium Yersinia pestis, there is surprisingly little information on the cellular and molecular …

Yersinia pestis Endowed with Increased Cytotoxicity Is Avirulent in a Bubonic Plague Model and Induces Rapid Protection against Pneumonic Plague

A Zauberman, A Tidhar, Y Levy, E Bar-Haim… - PLoS …, 2009 - journals.plos.org
An important virulence strategy evolved by bacterial pathogens to overcome host defenses
is the modulation of host cell death. Previous observations have indicated that Yersinia …