Nicotine exposure disrupts placental development via the Notch signaling pathway
QR Sun, DY Wu, JJ Zhang, LH Wu, X Zhang… - …, 2023 - rep.bioscientifica.com
In brief Normal gene expression during early embryonic development and in the placenta is
crucial for a successful pregnancy. Nicotine can disrupt normal gene expression during …
crucial for a successful pregnancy. Nicotine can disrupt normal gene expression during …
[PDF][PDF] Reduced placental size and increased apoptosis are associated with prenatal nicotine exposure in rats.
OBJECTIVE: Smoking during pregnancy has been linked to a variety of negative embryonic
and neonatal consequences. Nicotine is the major constituent of tobacco smoke, which was …
and neonatal consequences. Nicotine is the major constituent of tobacco smoke, which was …
Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies
AC Holloway, A Salomon, MJ Soares… - American Journal …, 2014 - journals.physiology.org
In utero exposure to nicotine is associated with increased risk of numerous adverse fetal and
neonatal outcomes, which suggests that it acts directly to affect placental development and …
neonatal outcomes, which suggests that it acts directly to affect placental development and …
Nicotine‐induced embryonic malformations mediated by apoptosis from increasing intracellular calcium and oxidative stress
Z Zhao, EA Reece - Birth Defects Research Part B …, 2005 - Wiley Online Library
BACKGROUND: Tobacco smoking by women during pregnancy increases the risk of
congenital birth defects in the infants. Among the smoke products, nicotine is believed to be …
congenital birth defects in the infants. Among the smoke products, nicotine is believed to be …
Adverse effects of perinatal nicotine exposure on reproductive outcomes
Nicotine exposure during pregnancy through cigarette smoking, nicotine replacement
therapies or e-cigarette use continues to be a widespread public health problem, impacting …
therapies or e-cigarette use continues to be a widespread public health problem, impacting …
Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta
MK Wong, CJ Nicholson, AC Holloway, DB Hardy - PloS one, 2015 - journals.plos.org
Maternal nicotine exposure has been associated with many adverse fetal and placental
outcomes. Although underlying mechanisms remain elusive, recent studies have identified …
outcomes. Although underlying mechanisms remain elusive, recent studies have identified …
Impact of Prenatal Nicotine Exposure on Placental Function and Respiratory Neural Network Development
S Beltrán-Castillo, K Bravo, J Eugenín - Advances in Maternal-Fetal …, 2023 - Springer
Smoking during pregnancy is associated with multiple undesirable outcomes in infants, such
as low birth weight, increased neonatal morbidity and mortality, and catastrophic conditions …
as low birth weight, increased neonatal morbidity and mortality, and catastrophic conditions …
Melatonin ameliorates murine fetal oocyte meiotic dysfunction in F1 and F2 offspring caused by nicotine exposure during pregnancy
WX Liu, SJ Tan, YF Wang, L Li, XF Sun, J Liu… - Environmental …, 2020 - Elsevier
Although there is abundant evidence to demonstrate that maternal smoking during
pregnancy will harm the health of future generations, the impact of nicotine use by pregnant …
pregnancy will harm the health of future generations, the impact of nicotine use by pregnant …
The impact of tobacco chemicals and nicotine on placental development
MA Suter, KM Aagaard - Prenatal diagnosis, 2020 - Wiley Online Library
Despite decades of messages warning about the dangers of tobacco use in pregnancy, 10%
to 15% of pregnant women continue to smoke. Furthermore, an increased popularity of …
to 15% of pregnant women continue to smoke. Furthermore, an increased popularity of …
Vitamin C supplementation ameliorates the adverse effects of nicotine on placental hemodynamics and histology in nonhuman primates
JO Lo, MC Schabel, VHJ Roberts, TK Morgan… - American journal of …, 2015 - Elsevier
Objective We previously demonstrated that prenatal nicotine exposure decreases neonatal
pulmonary function in nonhuman primates, and maternal vitamin C supplementation …
pulmonary function in nonhuman primates, and maternal vitamin C supplementation …
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