Modulation of the complement system in monocytes contributes to tuberculosis-associated immune reconstitution inflammatory syndrome

HTT Tran, R Van den Bergh, MM Loembé, W Worodria… - Aids, 2013 - journals.lww.com
Objective: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS)
is a common complication in HIV-TB co-infected patients receiving combined antiretroviral …

The role of monocytes in the development of Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome

HTT Tran, R Van den Bergh, TN Vu, K Laukens… - Immunobiology, 2014 - Elsevier
Abstract Background Tuberculosis-associated Immune Reconstitution Inflammatory
Syndrome (TB-IRIS) is a common complication of combined antiretroviral therapy (cART) in …

Biomarkers of CD4+ T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome

LA Chakrabarti, C Boucherie, F Bugault, MC Cumont… - Aids, 2014 - journals.lww.com
Objective: Patients coinfected with HIV and Mycobacterium tuberculosis frequently
experience a paradoxical worsening of tuberculosis (TB) symptoms early after the initiation …

Lower pre-treatment T cell activation in early-and late-onset tuberculosis-associated immune reconstitution inflammatory syndrome

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2015 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral …

Circulating inflammatory biomarkers can predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

LJ Haddow, O Dibben, MYS Moosa, P Borrow… - Aids, 2011 - journals.lww.com
Objective: To identify inflammatory biomarker profiles during paradoxical and unmasking
tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS), and …

LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2013 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) remains a poorly understood complication in HIV-TB co-infected patients initiating …

TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB

V Haridas, P Pean, LD Jasenosky, Y Madec… - Aids, 2015 - journals.lww.com
Objective: To investigate the impact of tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) upon immunological recovery and the T-cell compartment …

The immunopathogenesis of the HIV tuberculosis immune reconstitution inflammatory syndrome

RPJ Lai, JK Nakiwala, G Meintjes… - European journal of …, 2013 - Wiley Online Library
HIV‐1 patients co‐infected with some pathogens are at risk of developing the immune
reconstitution inflammatory syndrome (IRIS) when initiating antiretroviral therapy (ART). IRIS …

Interleukin-1 receptor antagonist, a biomarker of response to anti-TB treatment in HIV/TB co-infected patients

J Nouhin, P Pean, Y Madec, MF Chevalier, C Didier… - Journal of Infection, 2017 - Elsevier
Objectives Despite the high frequency of tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) in human immunodeficiency virus (HIV)/TB co-infected …

Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution …

PS Silveira-Mattos, G Narendran, K Akrami… - Scientific reports, 2019 - nature.com
Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-
infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy …