Tuberculosis-immune reconstitution inflammatory syndrome in HIV: from pathogenesis to prediction

N Gopalan, BB Andrade… - Expert review of clinical …, 2014 - Taylor & Francis
Tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is an exaggerated,
dysregulated immune response against dead or viable antigens of Mycobacterium …

Type 1 helper T cells and FoxP3-positive T cells in HIV–tuberculosis-associated immune reconstitution inflammatory syndrome

G Meintjes, KA Wilkinson, MX Rangaka… - American journal of …, 2008 - atsjournals.org
Rationale: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB–
IRIS) induced by combination antiretroviral therapy (cART) has been attributed to …

[HTML][HTML] Characteristics of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome and its influence on tuberculosis treatment outcomes in …

G Narendran, K Jyotheeswaran, T Senguttuvan… - International Journal of …, 2020 - Elsevier
Objective The influence of tuberculosis (TB)-immune reconstitution inflammatory syndrome
(IRIS) on TB treatment outcomes and its risk factors were investigated among people with …

[HTML][HTML] Transient expansion of activated CD8+ T cells characterizes tuberculosis-associated immune reconstitution inflammatory syndrome in patients with HIV: a …

E Espinosa, DP Romero-Rodríguez… - Journal of …, 2013 - Springer
Background CD4+ T cell activation indicators have been reported to be a common
phenomenon underlying diverse manifestations of immune reconstitution inflammatory …

[HTML][HTML] Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS

O Goovaerts, W Jennes, M Massinga-Loembe… - PLoS …, 2014 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral …

[HTML][HTML] TB-IRIS pathogenesis and new strategies for intervention: Insights from related inflammatory disorders

PM Cevaal, LG Bekker, S Hermans - Tuberculosis, 2019 - Elsevier
In almost one in five HIV/tuberculosis (TB) co-infected patients, initiation of antiretroviral
therapy (ART) is complicated by TB immune reconstitution inflammatory syndrome (TB-IRIS) …

Tuberculosis immune reconstitution inflammatory syndrome in A5221 STRIDE: timing, severity, and implications for HIV–TB programs

AF Luetkemeyer, MA Kendall, M Nyirenda… - JAIDS Journal of …, 2014 - journals.lww.com
Rationale and Objectives: Earlier initiation of antiretroviral therapy (ART) in HIV–tuberculosis
(TB) is associated with increased immune reconstitution inflammatory syndrome (IRIS). The …

Risk factors for 'unmasking immune reconstitution inflammatory syndrome'presentation of tuberculosis following combination antiretroviral therapy initiation in HIV …

N Valin, J Pacanowski, L Denoeud, K Lacombe… - Aids, 2010 - journals.lww.com
Objective: To determine characteristics and risk factors for unmasking tuberculosis (TB)-
associated immune reconstitution inflammatory syndrome (IRIS) following initiation of …

Clinical outcomes among HIV/tuberculosis-coinfected patients developing immune reconstitution inflammatory syndrome after HAART initiation in South India

N Kumarasamy, KK Venkatesh… - Journal of the …, 2013 - journals.sagepub.com
Introduction: We determine the frequency and immunological outcome of developing
immune reconstitution inflammatory syndrome (IRIS) among HIV/tuberculosis (TB) …

Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated …

S Ravimohan, N Tamuhla, K Nfanyana… - Clinical Infectious …, 2016 - academic.oup.com
Background. The immunopathogenesis of paradoxical tuberculosis-associated immune
reconstitution inflammatory syndrome (TB-IRIS) remains unclear. We determined the …