Microglia cells, the resident innate immune cells in the brain, are highly active, extending
and retracting highly motile processes through which they continuously survey their …

Parkinson's disease (PD) is an age-related neurodegenerative disease for which the
characteristic motor symptoms emerge after an extensive loss of dopamine containing …

Progressive loss of dopaminergic neurons in the substantia nigra pars compacta and their
terminal connections in the striatum are central features in Parkinson's disease (PD) …

Neuroinflammation is a hallmark of neurodegenerative diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). Microglia …

Despite wide genetic, environmental and clinical heterogeneity in amyotrophic lateral
sclerosis, a rapidly fatal neurodegenerative disease targeting motoneurons …

Microglia, the parenchymal brain macrophages of the central nervous system, have
emerged as critical players in brain development and homeostasis. The immune functions of …

Neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease
(AD) impose a pressing burden on our developed and consequently aging society …

Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

Parkinson's disease (PD) has classically been defined as a movement disorder, in which
motor symptoms are explained by the aggregation of alpha-synuclein (α-syn) and …

Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis
(ALS) is strongly associated with neuroinflammation reflected by activated microglia and …