Circadian rhythms coordinate our physiology at a fundamental level. Over the last 20 years,
we have witnessed a paradigm shift in our perception of what the clocks driving such …

The circadian clock is an endogenous, time-tracking system that directs multiple metabolic
and physiological functions required for homeostasis. The master or central clock located …

Over recent years, a deeper comprehension of the molecular mechanisms that control
biological clocks and circadian rhythms has been achieved. In fact, many studies have …

Daily and seasonal rhythms in the endocrine system are co-ordinated by a hypothalamic
pacemaker, the suprachiasmatic nuclei (SCN) that is synchronised to solar time by direct …

Circadian rhythms are generated by the autonomous circadian clock, the suprachiasmatic
nucleus (SCN), and clock genes that are present in all tissues. The SCN times these …

The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …

As a consequence of the Earth's rotation, almost all organisms experience day and night
cycles within a 24-hr period. To adapt and synchronize biological rhythms to external daily …

A plethora of physiological processes show stable and synchronized daily oscillations that
are either driven or modulated by biological clocks. A circadian pacemaker located in the …

Humans and other mammalian species possess an endogenous circadian clock system that
has evolved in adaptation to periodically reoccurring environmental changes and drives …

Circadian rhythms are daily cycles of physiology and behaviour that are driven by an
endogenous oscillator with a period of approximately (circa-) one day (diem). Exemplified in …