Impaired fatty acid metabolism in familial combined hyperlipidemia. A mechanism associating hepatic apolipoprotein B overproduction and insulin resistance.

MC Cabezas, TW De Bruin, HW De Valk… - The Journal of …, 1993 - Am Soc Clin Investig
To establish whether insulin resistance and/or postprandial fatty acid metabolism might
contribute to familial combined hyperlipidemia (FCH) we have examined parameters of …

Relationship of insulin sensitivity and ApoB levels to intra-abdominal fat in subjects with familial combined hyperlipidemia

JQ Purnell, SE Kahn, RS Schwartz… - … , and vascular biology, 2001 - Am Heart Assoc
Familial combined hyperlipidemia (FCHL) is one of the most common familial dyslipidemias
associated with premature heart disease. Subjects with FCHL typically have elevated …

Apolipoprotein, low density lipoprotein subfraction, and insulin associations with familial combined hyperlipidemia. Study of Utah patients with familial dyslipidemic …

SC Hunt, LL Wu, PN Hopkins, BM Stults… - … : An Official Journal of …, 1989 - Am Heart Assoc
Familial dyslipidemic hypertension (FDH) is a syndrome recently described from sibships
selected for early familial hypertension and found to have one or more of three fasting lipid …

Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia.

S Reynisdottir, M Eriksson, B Angelin… - The Journal of clinical …, 1995 - Am Soc Clin Investig
The pathophysiology of familial combined hyperlipidemia (FCHL) is unknown, but altered
lipid turnover in peripheral tissues as well as hepatic overproduction of apolipoprotein B …

Defects of insulin action on fatty acid and carbohydrate metabolism in familial combined hyperlipidemia

TJ Aitman, IF Godsland, B Farren, D Crook… - … , and vascular biology, 1997 - Am Heart Assoc
Familial combined hyperlipidemia (FCHL) is a common cause of premature myocardial
infarction, but its metabolic basis is unknown. Insulin resistance has been suggested in …

Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia

A CHAIT, JJ ALBERS… - European journal of …, 1980 - Wiley Online Library
Very low density lipoprotein kinetic parameters were compared in familial
hypertriglyceridaemia and familial combined hyperlipidaemia, two distinct genetic forms of …

Postprandial apolipoprotein B100 and B48 metabolism in familial combined hyperlipidaemia before and after reduction of fasting plasma triglycerides

MC Cabezas, DW Erkelens, LAW Kock… - European journal of …, 1994 - Wiley Online Library
Hepatic VLDL overproduction in familial combined hyperlipidaemia (FCH) may delay the
clearance of atherogenic apolipoprotein (apo) B containing particles. We investigated if …

Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex

EM Wijsman, JD Brunzell, GP Jarvik… - … , and vascular biology, 1998 - Am Heart Assoc
Familial combined hyperlipidemia (FCHL) was originally described as a disorder
characterized by elevated levels of either plasma cholesterol or triglyceride (TG) or both in …

Lipoprotein and apolipoprotein abnormalities in familial combined hyperlipidemia: a 20-year prospective study

MJ McNeely, KL Edwards, SM Marcovina, JD Brunzell… - Atherosclerosis, 2001 - Elsevier
In order to characterize the lipoprotein abnormalities in familial combined hyperlipidemia
(FCHL) and to describe factors associated with the stability of the FCHL phenotype during …

[HTML][HTML] Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia

JD Brunzell, JJ Albers, A Chait, SM Grundy… - Journal of lipid …, 1983 - Elsevier
Plasma lipoprotein concentration, composition, and size were evaluated in two common
familial forms of hypertriglyceridemia and compared with those in normal subjects. The very …