This study aimed to examine the validity of urinary N-terminal titin fragment/creatinine
(urinary N-titin/Cr) reflecting muscle damage biomarker in patients with interstitial lung …

Background: Few non-invasive biomarkers have been used to detect myocardial injury in
patients with heart diseases. Recently, the N-terminal fragment (N-titin) of titin, a giant …

Early detection of skeletal muscle atrophy is important to prevent further muscle weakness.
However, there are few non-invasive biomarkers for skeletal muscle atrophy. Recent studies …

Titin is a giant protein that functions as a molecular spring in sarcomeres. Titin interconnects
the contraction of actin-containing thin filaments and myosin-containing thick filaments. Titin …

The differential diagnosis of cardiomyopathy is important. It has been recently reported that
urinary titin N (U-TN) is increased in patients with muscular dystrophy (MD), and is …

Titin is a giant protein that is specifically expressed in striated muscle and essential for the
maintenance of sarcomere structure and function. Recently, the N-terminal fragment of the …

Objectives: Although skeletal muscle atrophy is common in critically ill patients, biomarkers
associated with muscle atrophy have not been identified reliably. Titin is a spring-like protein …

Titin, encoded by the gene TTN, is the largest human protein, and plays central roles in
sarcomeric structures and functions in skeletal and cardiac muscles. Mutations of TTN are …

Enzyme-linked and electrochemiluminescence immunoassays were developed for
quantification of amino (N-) terminal fragments of the skeletal muscle protein titin (N-ter titin) …

Many studies have attempted to determine the associations between blood biomarkers and
exercise-induced muscle damage. However, poor correlations between the changes in …