Group II introns contain a large ribozyme, which catalyzes self-splicing, and the coding
sequence of a reverse transcriptase, the function of which is to cooperate with the ribozyme …

The upstream site of cleavage of all group I self-splicing introns is identified by an absolutely
conserved U· G base pair. Although a wobble C· A pair can substitute the U· G pair, all other …

The splicing process catalyzed by group II intron ribozymes follows the same two-step
pathway as nuclear pre-mRNA splicing. In vivo, the first splicing step of wild-type introns is a …

Group II introns are mobile genetic elements that have been implicated as agents of genetic
diversity, and serve as important model systems for investigating RNA catalysis and pre …

Group II introns are self-splicing ribozymes that share a reaction mechanism and a common
ancestor with the eukaryotic spliceosome, thereby providing a model system for …

The identical reaction pathway executed by the spliceosome and self-splicing group II intron
ribozymes has prompted the idea that both may be derived from a common molecular …

Group I and group II introns are two types of RNA enzymes, ribozymes, that catalyze their
own splicing by different mechanisms. In this review, we summarize current information …

Group II introns are large, natural catalytic RNAs or ribozymes that were discovered in
organelles of certain protists, fungi, algae, and plants and more recently also in prokaryotic …

Group II introns are found in eubacteria and eubacterial-derived, organellar genomes. They
have ribozymic activities, by which they direct and catalyze the splicing of the exons flanking …

Divalent metal ions are required for splicing of group I introns, but their role in maintaining
the structure of the active site is still under investigation. Ribonuclease and hydroxyl radical …