Isorhynchophylline (Isorhy) is one of the major alkalords extracted from Chinese traditional
medicine, Uncaria rhynchophylla (Mip). Jackson. By using atrial pacing and recording His …

As one important constituent extracted from a traditional Chinese medicine, Uncaria
rhynchophylla Miq Jacks, isorhynchophylline has been used to treat hypertension, epilepsy …

The pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline
extracted from Uncaria rhynchophylla Miq Jacks were reviewed. The alkaloids mainly act on …

The effects of hirsutine, an indole alkaloid from Uncaria rhynchophylla MIQ. JACKSON with
antihypertensive, negative chronotropic and antiarrhythmic activity, and its C3 structural …

Rhynchophylline (Rhy, 2.5-25mg/kg, iv) dose-dependently decreased the heart rate,
prolonged PR, QT interval and widened QRS wares in anaesthetized rat^ s ECG. These …

We investigated the action of two synthetic isoquinoline alkaloids, 3, 4-dihydroxybenzyl-6, 7-
dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (CSH109) and 2-bromo-3, 4-dimethoxybenzyl 6 …

Antiarrhythmic effect of isoliensinine (IL) was studied on experimental arrhythmic mo-dels
induced by coronary artery ligation and 4 different arrhythmogenic drugs in comparison with …

Pharmacological studies on hirsutine (HS), hirsuteine (HST), rhynchophylline (RP),
isorhynchophylline (IRP) and dihydrocorynantheine (DCT) which were isolated from the …

Higenamine is a potent cardiotonic benzylisoquinoline alka-loid, isolated from the root of
Aconitum japonicum Thunb.(Ranunclaceae)(1, 2), and also from several other natural prod …

Isorhynchophylline (Iso) inhibits the automaticity and contractile force of isolated guinea pig
atrium in a concentration-dependent manner, 30 mumol/L markedly depresses adrenaline …