Background Systemic amyloidosis is a multi-system disease caused by fibrillary protein
deposition with ensuing dysfunction of the affected organ systems. Its diagnosis is often …

The systemic amyloidoses are a group of diseases characterized by the deposition of
amyloid, a material formed from misfolding of proteins, in one or more organs. The 2 …

Background Amyloidosis is considered a rare heterogeneous condition comprising different
entities. Epidemiological data are limited and often controversial. We aimed to examine …

Amyloid transthyretin (ATTR) amyloidosis is a clinically heterogeneous and fatal disease
that results from deposition of insoluble amyloid fibrils in various organs and tissues …

Importance Many patients with systemic amyloidosis are underdiagnosed. Overall, 25% of
patients with immunoglobulin light chain (AL) amyloidosis die within 6 months of diagnosis …

Background Hereditary transthyretin-mediated amyloidosis, also known as ATTRv
amyloidosis (v for variant), is a rare, autosomal dominant, fatal disease, in which systemic …

Amyloidoses are characterized by the tissue accumulation of misfolded proteins into
insoluble fibrils. The two most common types of systemic amyloidosis result from the …

Purpose Amyloidosis represents an increasingly recognized but still frequently missed
cause of heart failure. In the light of many effective therapies for light chain (AL) amyloidosis …

Amyloidosis is a collection of systemic diseases characterised by misfolding of previously
soluble precursor proteins that become infiltrative depositions, thereby disrupting normal …

Aims Transthyretin amyloidosis (ATTR amyloidosis) is a heterogeneous disorder with
cardiac, neurologic, and mixed phenotypes. We describe the phenotypic and genotypic …