New therapeutics based on emerging concepts in pulmonary fibrosis

V Sontake, PR Gajjala, RK Kasam… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Fibrosis is an irreversible pathological endpoint in many chronic diseases,
including pulmonary fibrosis. Idiopathic pulmonary fibrosis (IPF) is a progressive and often …

Idiopathic pulmonary fibrosis: pathobiology of novel approaches to treatment

TM Maher - Clinics in chest medicine, 2012 - chestmed.theclinics.com
Idiopathic pulmonary fibrosis is a nonmalignant disease, yet it carries a prognosis akin to, or
even worse than, many cancers. Until recently, lung transplantation has been the only …

Idiopathic pulmonary fibrosis: Molecular mechanisms and potential treatment approaches

DS Glass, D Grossfeld, HA Renna, P Agarwala… - Respiratory …, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with high mortality that
commonly occurs in middle-aged and older adults. IPF, characterized by a decline in lung …

[HTML][HTML] The treatment of idiopathic pulmonary fibrosis

HV Woodcock, TM Maher - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a progressive and invariably fatal disease with a
median survival of less than three years from diagnosis. The last decade has seen an …

Idiopathic pulmonary fibrosis: an update

P Spagnolo, N Sverzellati, G Rossi, A Cavazza… - Annals of …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic
interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults …

A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials

HR Collard, WZ Bradford, V Cottin… - European …, 2015 - Eur Respiratory Soc
The past decade has seen substantial progress in understanding the pathobiology, natural
history, and clinical significance of idiopathic pulmonary fibrosis (IPF), culminating in the …

Idiopathic pulmonary fibrosis: pathogenesis and management

G Sgalla, B Iovene, M Calvello, M Ori, F Varone… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease
characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma …

Pathogenesis, current treatments and future directions for idiopathic pulmonary fibrosis

H Loomis-King, KR Flaherty, BB Moore - Current opinion in pharmacology, 2013 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease (ILD) of unknown
origin characterized by epithelial cell dysfunctions, accumulation of fibroblasts and …

Pharmacological treatment of idiopathic pulmonary fibrosis: from the past to the future

KM Antoniou, GA Margaritopoulos… - European Respiratory …, 2013 - Eur Respiratory Soc
During the past decade important progress has been made regarding the pathogenesis of
idiopathic pulmonary fibrosis (IPF), which is the most devastating form of idiopathic …

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

KM Antoniou, A Pataka, D Bouros… - Pulmonary pharmacology …, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a poorly understood disease that usually leads to death
within 5 years of diagnosis. Despite our better understanding of IPF pathogenesis, the …