The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation
W Alasmari, CLR Barratt, SJ Publicover… - Human …, 2013 - academic.oup.com
STUDY QUESTION What is the prevalence of defects in the Ca2+-signalling pathways
mediating hyperactivation (calcium influx and store mobilization) among donors and sub …
mediating hyperactivation (calcium influx and store mobilization) among donors and sub …
Capacitation increases glucose consumption in murine sperm
Mammalian sperm acquire fertilization capacity in the female reproductive tract in a process
known as capacitation. During capacitation, sperm change their motility pattern (ie …
known as capacitation. During capacitation, sperm change their motility pattern (ie …
The CatSper calcium channel in human sperm: relation with motility and involvement in progesterone-induced acrosome reaction
Abstract STUDY QUESTION Does CatSper have a role in the achievement of human sperm
motility and in the Progesterone (P)-induced acrosome reaction (AR)? SUMMARY ANSWER …
motility and in the Progesterone (P)-induced acrosome reaction (AR)? SUMMARY ANSWER …
[HTML][HTML] Influence of antifertility agents Dutasteride and Nifedipine on CatSper gene level in epididymis during sperm maturation in BALB/c mice
A Srivastav, B Changkija, K Sharan, GK Nagar… - …, 2018 - rep.bioscientifica.com
Calcium (Ca 2+) signaling is critical for successful fertilization. In spermatozoa, capacitation,
hyperactivation of motility and the acrosome reaction are all mediated by increases in …
hyperactivation of motility and the acrosome reaction are all mediated by increases in …
[HTML][HTML] Release of porcine sperm from oviduct cells is stimulated by progesterone and requires CatSper
Sperm storage in the female reproductive tract after mating and before ovulation is a
reproductive strategy used by many species. When insemination and ovulation are poorly …
reproductive strategy used by many species. When insemination and ovulation are poorly …
[HTML][HTML] CCR6 is required for ligand-induced CatSper activation in human sperm
CatSper channel has been considered the principal sperm Ca 2+ channel responsible for
the cytosolic Ca 2+ elevation required for various sperm functions necessary for fertilization …
the cytosolic Ca 2+ elevation required for various sperm functions necessary for fertilization …
[HTML][HTML] Comparative genomic analysis suggests that the sperm-specific sodium/proton exchanger and soluble adenylyl cyclase are key regulators of CatSper among …
F Romero, T Nishigaki - Zoological Letters, 2019 - Springer
Background CatSper is a sperm-specific calcium ion (Ca 2+) channel, which regulates
sperm flagellar beating by tuning cytoplasmic Ca 2+ concentrations. Although this Ca 2+ …
sperm flagellar beating by tuning cytoplasmic Ca 2+ concentrations. Although this Ca 2+ …
Regulation of ion and ion channels in sperm capacitation
SX Zhang, XY Liu, HY Wang - … nan ke xue= National Journal of …, 2009 - europepmc.org
Ion channels in mammal sperm, including Ca2+, Na+, K+, Cl-and HCO3-channels, each
play a key role in the process of sperm capacitation. Ca2+, HCO3-and ROS, as signal …
play a key role in the process of sperm capacitation. Ca2+, HCO3-and ROS, as signal …
[HTML][HTML] CatSper mediates not only chemotactic behavior but also the motility of ascidian sperm
T Kijima, D Kurokawa, Y Sasakura… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Sperm motility, including chemotactic behavior, is regulated by changes in the
intracellular Ca2+ concentration, and the sperm-specific Ca2+ channel CatSper has been …
intracellular Ca2+ concentration, and the sperm-specific Ca2+ channel CatSper has been …
[HTML][HTML] 3D structure and in situ arrangements of CatSper channel in the sperm flagellum
The sperm calcium channel CatSper plays a central role in successful fertilization as a
primary Ca2+ gateway. Here, we applied cryo-electron tomography to visualize the higher …
primary Ca2+ gateway. Here, we applied cryo-electron tomography to visualize the higher …