Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
I Zachary - American Journal of Physiology-Cell Physiology, 2001 - journals.physiology.org
Vascular endothelial growth factor (VEGF) is essential for angiogenesis in health and
pathophysiology, and it is currently a major focus for drug targeting in the development of …
pathophysiology, and it is currently a major focus for drug targeting in the development of …
Vascular protection: a novel nonangiogenic cardiovascular role for vascular endothelial growth factor
I Zachary, A Mathur, S Yla-Herttuala… - … , and vascular biology, 2000 - Am Heart Assoc
There is widespread interest in the use of the angiogenic cytokine, vascular endothelial
growth factor (VEGF), for the treatment of cardiovascular disease. The main paradigm for …
growth factor (VEGF), for the treatment of cardiovascular disease. The main paradigm for …
Signaling pathways induced by vascular endothelial growth factor
B Larrivee, A Karsan - International journal of …, 2000 - spandidos-publications.com
Vasculogenesis and angiogenesis are the mechanisms responsible for the development of
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …
Vascular endothelial growth factor and angiogenesis
ANN Hoeben, B Landuyt, MS Highley, H Wildiers… - Pharmacological …, 2004 - ASPET
Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …
Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction
CK Domigan, S Ziyad… - … , thrombosis, and vascular …, 2015 - Am Heart Assoc
The past 5 years have witnessed a significant expansion in our understanding of vascular
endothelial growth factor (VEGF) signaling. In particular, the process of canonical activation …
endothelial growth factor (VEGF) signaling. In particular, the process of canonical activation …
Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine
S Ylä-Herttuala, TT Rissanen, I Vajanto… - Journal of the american …, 2007 - jacc.org
Members of the vascular endothelial growth factor (VEGF) family are among the most
powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and …
powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and …
[HTML][HTML] Autocrine VEGF signaling is required for vascular homeostasis
Vascular endothelial growth factor (VEGF) is essential for developmental and pathological
angiogenesis. Here we show that in the absence of any pathological insult, autocrine VEGF …
angiogenesis. Here we show that in the absence of any pathological insult, autocrine VEGF …
Basic science review: current insights on the biology and clinical aspects of VEGF regulation
Vascular endothelial growth factor (VEGF) is a key molecule that orchestrates the formation
and function of vascular networks. Impaired regulation of angiogenesis is implicated in a …
and function of vascular networks. Impaired regulation of angiogenesis is implicated in a …
VEGF receptor signaling and endothelial function
S Kliche, J Waltenberger - IUBMB life, 2001 - Wiley Online Library
Angiogenesis, the formation of new blood vessels from preexisting ones, is a central process
during normal development and during pathological repair. Vascular endothelial growth …
during normal development and during pathological repair. Vascular endothelial growth …
Vascular endothelial growth factor-B promotes in vivo angiogenesis
JS Silvestre, R Tamarat, TG Ebrahimian… - Circulation …, 2003 - Am Heart Assoc
Vascular endothelial growth factors (VEGFs) and their receptors have emerged as central
regulators of the angiogenic process. However, involvement of VEGF-B, one of these factors …
regulators of the angiogenic process. However, involvement of VEGF-B, one of these factors …