Background: The therapeutic reference range for venlafaxine in antidepressant treatment
has been defined as 100 to 400 ng/mL. However, in an everyday setting active moiety …

Venlafaxine is a commonly used antidepressant agent. We aimed to provide detailed
information on the associations between venlafaxine dose and concentrations of …

Introduction The selective serotonin and norepinephrine reuptake inhibitor venlafaxine is
among the most prescribed antidepressant drugs worldwide and, according to guidelines, its …

Objective: Venlafaxine (VEN) is a widely used antidepressant drug, which is available in
both brand-name and generic formulations. Bioequivalence studies indicate some …

Introduction: Early assessment of a therapeutic response is a central goal in antidepressant
treatment. The present study examined the potential for therapeutic drug monitoring and …

Venlafaxine, a dual serotonin and noradrenaline re-uptake inhibitor, has been found to be
effective at doses below 375 mg daily, but for patients with major depression higher doses …

High doses of antidepressants are often used for treatment-resistant depression.
Venlafaxine, a dual serotonin and noradrenaline reuptake inhibitor, has been shown to have …

Abstract Background Therapeutic Drug Monitoring (TDM) represents one of the most
promising tools in clinical practice to optimise antidepressant treatment. Nevertheless, little …

Objective: To investigate whether drug concentrations of venlafaxine and its metabolite O-
desmethylvenlafaxine in plasma can be considered as a surrogate marker of concentrations …

Purpose To assess in a large naturalistic sample, whether clinical response to a treatment
with venlafaxine is associated with different patterns of plasma concentrations of active …