Natural T-cell Response against MHC Class I Epitopes of Epithelial Cell Adhesion Molecule, her-2/neu, and Carcinoembryonic Antigen in Patients with Colorectal …
D Nagorsen, U Keilholz, L Rivoltini, A Schmittel… - Cancer research, 2000 - AACR
The antigens epithelial cell adhesion molecule (Ep-CAM), her-2/neu, and carcinoembryonic
antigen (CEA) are potential T-cell targets in antigen-specific vaccination-based cancer …
antigen (CEA) are potential T-cell targets in antigen-specific vaccination-based cancer …
Phase I/II multicenter trial of a novel therapeutic cancer vaccine, HepaVac-101, for hepatocellular carcinoma
MW Löffler, S Gori, F Izzo, A Mayer-Mokler… - Clinical Cancer …, 2022 - AACR
Purpose: Immunotherapy for hepatocellular carcinoma (HCC) shows considerable promise
in improving clinical outcomes. HepaVac-101 represents a single-arm, first-in-human phase …
in improving clinical outcomes. HepaVac-101 represents a single-arm, first-in-human phase …
Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells
R Schroers, XF Huang, J Hammer, J Zhang, SY Chen - Cancer research, 2002 - AACR
CD4+ T cells play critical roles in initiating, regulating, and maintaining antitumor
immuneresponses. One way to improve current tumor vaccines that mainly induce CTLs …
immuneresponses. One way to improve current tumor vaccines that mainly induce CTLs …
Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor
M Dosset, Y Godet, C Vauchy, L Beziaud, YC Lone… - Clinical Cancer …, 2012 - AACR
Purpose: To evaluate CD4+ helper functions and antitumor effect of promiscuous universal
cancer peptides (UCP) derived from telomerase reverse transcriptase (TERT). Experimental …
cancer peptides (UCP) derived from telomerase reverse transcriptase (TERT). Experimental …
Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells …
A Lev, G Denkberg, CJ Cohen, M Tzukerman… - Cancer research, 2002 - AACR
The recent characterization of MHC-displayed tumor-associated antigensthat recognize
effector cells of the immune system has created new perspectives for cancer therapy …
effector cells of the immune system has created new perspectives for cancer therapy …
Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals
RH Vonderheide, JL Schultze, KS Anderson… - Cancer Research, 2001 - AACR
Although high frequencies of T lymphocytes specific for certain tumor-associated antigens
have been detected in some cancer patients, increasing evidence suggests that these T …
have been detected in some cancer patients, increasing evidence suggests that these T …
Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
EM Inderberg-Suso, S Trachsel, K Lislerud… - …, 2012 - Taylor & Francis
Understanding the basis of a successful clinical response after treatment with therapeutic
cancer vaccines is essential for the development of more efficacious therapy. After …
cancer vaccines is essential for the development of more efficacious therapy. After …
HLA‐A2‐restricted CTL epitopes of a novel lung cancer‐associated cancer testis antigen, cell division cycle associated 1, can induce tumor‐reactive CTL
M Harao, S Hirata, A Irie, S Senju… - … journal of cancer, 2008 - Wiley Online Library
Toward the development of a novel cancer immunotherapy, we have previously identified
several tumor‐associated antigens (TAAs) and the epitopes recognized by human …
several tumor‐associated antigens (TAAs) and the epitopes recognized by human …
[HTML][HTML] Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients
XY Dong, YR Su, XP Qian, XA Yang, XW Pang… - British journal of …, 2003 - nature.com
FATE and TPTE genes were originally reported to be specifically expressed in the adult
testis. We searched for the databases of Unigene and serial analysis of gene expression …
testis. We searched for the databases of Unigene and serial analysis of gene expression …
Analysis of spontaneous tumor-specific CD4 T-cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with …
Y Godet, E Fabre, M Dosset, M Lamuraglia… - Clinical Cancer …, 2012 - AACR
Purpose: To investigate the presence and impact of spontaneous telomerase-specific CD4 T-
cell responses in cancer patients. Experimental Design: A multistep approach was used to …
cell responses in cancer patients. Experimental Design: A multistep approach was used to …