[HTML][HTML] Nigella sativa as an anti-inflammatory and promising remyelinating agent in the cortex and hippocampus of experimental autoimmune encephalomyelitis …

HM Fahmy, NA Noor, FF Mohammed… - The Journal of Basic & …, 2014 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is a well-established animal model of
multiple sclerosis. This study aimed to investigate the protective and therapeutic effects of …

Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB …

MK Cobourne-Duval, E Taka, P Mendonca… - Journal of …, 2018 - Elsevier
Neuroinflammation and microglial activation are pathological markers of a number of central
nervous system (CNS) diseases. Chronic activation of microglia induces the release of …

[HTML][HTML] Neuroprotective effects of Nigella sativa extracts during germination on central nervous system

MH Islam, IZ Ahmad, MT Salman - Pharmacognosy magazine, 2015 - ncbi.nlm.nih.gov
Background: Nigella sativa Linn. which has many acclaimed medicinal properties is an
indigenous herbaceous plant and belongs to the Ranunculaceae family, which grows in …

Medicinal and phamacological potential of nigella sativa: a review

NK Sharma, D Ahirwar, D Jhade… - Ethnobotanical …, 2009 - opensiuc.lib.siu.edu
Herbs are vital source of drugs from the ancient time holding the scenario of the Indian
system of medicine. Nigella sativa commonly known as karayal is an annual flowering plant …

Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Nigella sativa: Holy Herb of the Middle East

E Yarnell, K Abascal - Alternative and complementary Therapies, 2011 - liebertpub.com
Nigella sativa (black seed or black cumin) originated from the Mediterranean region and has
been used in cultures in that area since time immemorial. The well-named herb has jetblack …

[PDF][PDF] Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats

A Al-Ali, AA Alkhawajah, MA Randhawa… - J Ayub Med Coll …, 2008 - researchgate.net
Background: Thymoquinone is the major active principle of Nigella sativa (N. sativa) and
constitutes about 30% of its volatile oil or ether extract. N. sativa oil and seed are commonly …

[HTML][HTML] An overview on cardioprotective and anti-diabetic effects of thymoquinone

T Farkhondeh, S Samarghandian, A Borji - Asian Pacific journal of tropical …, 2017 - Elsevier
Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many
biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant …

Thymoquinone: potential cure for inflammatory disorders and cancer

CC Woo, AP Kumar, G Sethi, KHB Tan - Biochemical pharmacology, 2012 - Elsevier
Thymoquinone is an active ingredient isolated from Nigella sativa and has been
investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro …

Nigella sativa: monograph

S Sultana, HM Asif, N Akhtar, A Iqbal… - Journal of …, 2015 - phytojournal.com
Nigella sativa (N. sativa)(Family Ranunculaceae) have been used for thousands of years as
a curative remedy for various disorders. N. sativa seed reveal a broad spectrum of …