Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Insight into the mammalian aquaporin interactome

S Törnroth-Horsefield, C Chivasso… - International journal of …, 2022 - mdpi.com
Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living
organisms. AQPs facilitate osmotically driven water flux across biological membranes and …

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

P Kitchen, RE Day, MM Salman, MT Conner… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background Aquaporin (AQP) water channels are best known as passive transporters of
water that are vital for water homeostasis. Scope of review AQP knockout studies in whole …

Aquaporins: a promising target for drug development

K Jeyaseelan, S Sepramaniam… - Expert opinion on …, 2006 - Taylor & Francis
Aquaporins (AQPs) are a family of small hydrophobic, integral membrane proteins that are
expressed in all living organisms and play critical roles in controlling the water flow into and …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Novel roles of aquaporins revealed by phenotype analysis of knockout mice

AS Verkman - Reviews of physiology biochemistry and pharmacology, 2004 - Springer
The aquaporins (AQPs) are small integral membrane proteins that transport water and in
some cases small solutes such as glycerol. Physiological roles of the ten or more …

Structure and function of aquaporin water channels

AS Verkman, AK Mitra - American Journal of Physiology …, 2000 - journals.physiology.org
The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size∼
30 kDa) that are expressed at plasma membranes in many cells types involved in fluid …

Aquaporins in renal diseases

J He, B Yang - International journal of molecular sciences, 2019 - mdpi.com
Aquaporins (AQPs) are a family of highly selective transmembrane channels that mainly
transport water across the cell and some facilitate low-molecular-weight solutes. Eight AQPs …

Aquaporins: phylogeny, structure, and physiology of water channels

JB Heymann, A Engel - Physiology, 1999 - journals.physiology.org
How water permeates cellular membranes and what this means for cell functioning and
several diseases are now emerging from the study of the aquaporins (AQPs), the water …

Localization and trafficking of aquaporin 2 in the kidney

K Takata, T Matsuzaki, Y Tajika, A Ablimit… - Histochemistry and cell …, 2008 - Springer
Aquaporins (AQPs) are membrane proteins serving in the transfer of water and small solutes
across cellular membranes. AQPs play a variety of roles in the body such as urine formation …