Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very
dynamic tissue subjected to continuous remodeling in order to preserve its structure and …

The regenerative medicine, a new discipline that merges biological sciences and the
fundamental of engineering to develop biological substitutes, has greatly benefited from …

Bone is a dynamic tissue that can always rebuild itself by modeling and remodeling to
maintain functionality. This tissue is responsible for several vital functions in the body, such …

Bone tissue has the capability to regenerate itself; however, defects of a critical size prevent
the bone from regenerating and require additional support. To aid regeneration, bone …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Abstract The role of Bone Tissue Engineering in the field of Regenerative Medicine has
been the topic of substantial research over the past two decades. Technological advances …

Bone provides mechanical support, and flexibility to the body as a structural frame work
along with mineral storage, homeostasis, and blood pH regulation. The repair and/or …

The management of bone defects is complicated by the presence of clinical conditions, such
as critical-sized defects created by high-energy trauma, tumour resection, infection, and …

The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

The treatment of bone defects remains one of the major challenges in modern clinical
practice. Nowadays, with the increased incidence of bone disease in an aging population …