Macroscale biomaterials strategies for local immunomodulation
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …
manipulation of innate and adaptive immune responses is of great promise for a wide array …
Biomaterials as local niches for immunomodulation
K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Immunomodulatory biomaterials for tissue repair
R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
Biomaterial strategies for immunomodulation
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …
importance for diverse biomedical applications, such as the development of new vaccines …
Materials for immunotherapy
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …
preclinical studies. The interplay of chemistry and materials has resulted in improved …
Biomaterials-mediated engineering of the immune system
C Backlund, S Jalili-Firoozinezhad… - Annual review of …, 2023 - annualreviews.org
Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
Biomaterial-assisted macrophage cell therapy for regenerative medicine
S Sung, LA Steele, GE Risser, KL Spiller - Advanced drug delivery reviews, 2023 - Elsevier
Although most tissue types are capable of some form of self-repair and regeneration, injuries
that are larger than a critical threshold or those occurring in the setting of certain diseases …
that are larger than a critical threshold or those occurring in the setting of certain diseases …
Biomaterials for enhancing anti-cancer immunity
Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …
Advances in immunotherapy delivery from implantable and injectable biomaterials
Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …