Naringin exhibited therapeutic effects against DSS-induced mice ulcerative colitis in intestinal barrier–dependent manner

R Cao, X Wu, H Guo, X Pan, R Huang, G Wang, J Liu - Molecules, 2021 - mdpi.com
Naringin is a kind of multi-source food additive which has been explored broadly for its
various biological activities and therapeutic potential. In the present study, the protective …

Protective effect of naringin on DSS-induced ulcerative colitis in mice

H Cao, J Liu, P Shen, J Cai, Y Han, K Zhu… - Journal of agricultural …, 2018 - ACS Publications
Peroxisome proliferator-activated receptor γ (PPARγ) is an important member of the nuclear
receptor superfamily. Previous studies have shown the satisfactory anti-inflammatory role of …

Naringin exerts therapeutic effects on mice colitis: a study based on transcriptomics combined with functional experiments

J Dong, Y Chen, F Yang, W Zhang, K Wei… - Frontiers in …, 2021 - frontiersin.org
Naringin has been shown to exert protective effects in an animal model of ulcerative colitis,
but detailed mechanisms remain unclear. This study aimed to investigate function and …

The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice

Y Zhang, O Wang, N Ma, J Yi, H Mi, S Cai - Food & Function, 2021 - pubs.rsc.org
The purpose of this research was to explore the preventive effect of an 80% ethanol extract
of Rhus chinensis Mill. fruits on dextran sulfate sodium (DSS)-induced colitis in mice and to …

Hydroxysafflor yellow A protects against ulcerative colitis via suppressing TLR4/NF‐κB signaling pathway

Z Feng, P Zhou, X Wu, J Zhang… - Chemical Biology & …, 2022 - Wiley Online Library
Hydroxysafflower yellow A (HSYA) protects against acute kidney injury through TLR4/NF‐κB
pathway. However, the effect and potential mechanism of HSYA in ulcerative colitis (UC) …

Naringin mitigates LPS-induced intestinal barrier injury in mice

D Luo, Z Huang, G Jia, H Zhao, G Liu, X Chen - Food & Function, 2023 - pubs.rsc.org
The aim of this study was to investigate the effect of naringin on lipopolysaccharide (LPS)-
induced jejunal barrier function in mice. Forty-five 3-week-old healthy male Balb/c mice with …

[HTML][HTML] Improved colonic inflammation by nervonic acid via inhibition of NF-κB signaling pathway of DSS-induced colitis mice

SN Yuan, M Wang, JL Han, CY Feng, M Wang… - Phytomedicine, 2023 - Elsevier
Abstract Background Nervonic acid (C24: 1∆ 15, 24: 1 ω-9, cis-tetracos-15-enoic acid; NA), a
long-chain monounsaturated fatty acid, plays an essential role in prevention of metabolic …

[HTML][HTML] Antioxidation and anti-inflammatory actions of the extract of Nitraria Tangutorum Bobr. fruits reduce the severity of ulcerative colitis in a dextran sulphate …

Q Zou, J Feng, T Li, G Cheng, W Wang, G Rao… - Journal of Functional …, 2022 - Elsevier
In the present study, we characterised 25 compounds in the extract of Nitraria Tangutorum
Bobr. fruits by using the HPLC/MS/MS method. We determined the antioxidant activities of …

Dietary tangeretin alleviated dextran sulfate sodium-induced colitis in mice via inhibiting inflammatory response, restoring intestinal barrier function, and modulating …

B Chen, J Luo, Y Han, H Du, J Liu, W He… - Journal of Agricultural …, 2021 - ACS Publications
In this study, the preventive effect of tangeretin (TAN), a natural flavonoid derivative from
citrus fruits, on the dextran sulfate sodium (DSS)-induced colitis in mice was evaluated. Our …

Black rice anthocyanin-rich extract and rosmarinic acid, alone and in combination, protect against DSS-induced colitis in mice

L Zhao, Y Zhang, G Liu, S Hao, C Wang, Y Wang - Food & function, 2018 - pubs.rsc.org
The aim of this study was to investigate the effect of black rice anthocyanin-rich extract
(BRAE) and rosmarinic acid (RA), alone and in combination, on dextran sulfate sodium …