Antibiotic decision-making in the ICU

L Parra-Rodriguez… - Seminars in Respiratory …, 2022 - thieme-connect.com
It is well established that Intensive Care Units (ICUs) are a focal point in antimicrobial
consumption with a major influence on the ecological consequences of antibiotic use. With …

Rationalizing antimicrobial therapy in the ICU: a narrative review

JF Timsit, M Bassetti, O Cremer, G Daikos… - Intensive care …, 2019 - Springer
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

Antibiotic use in the intensive care unit: optimization and de-escalation

M Campion, G Scully - Journal of intensive care medicine, 2018 - journals.sagepub.com
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes.
Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay …

Reducing antibiotic use in the ICU: a time-based approach to rational antimicrobial use

PO Depuydt, L De Bus, JJ De Waele - Annual Update in Intensive Care …, 2016 - Springer
Antibiotics are life-saving drugs and among the most important therapeutic weapons of the
intensive care unit (ICU) physician. In severe bacterial infection, community-acquired …

Antibiotic therapy in the critically ill-expert opinion of the Intensive Care Medicine Scientific Subcommittee of the European Society of Anaesthesiology

I Martin-Loeches, M Leone, K Madach… - European Journal of …, 2017 - journals.lww.com
Antimicrobial treatment is the cornerstone of infection treatment, and the selection of
appropriate antibiotic treatment for critically ill patients is challenging. Clinicians working …

Rational empiric antibiotic prescription in the ICU

N Singh, LY Victor - Chest, 2000 - Elsevier
The prescribing of antibiotics in the ICU is usually empiric, given the critical nature of the
conditions of patients hospitalized there. Appropriate antibiotic utilization in this setting is …

A practical approach to clinical antibiotic stewardship in the ICU patient with severe infection

J Fierens, PO Depuydt… - Seminars in Respiratory …, 2019 - thieme-connect.com
Patients with severe infections are often treated with multiple courses of antibiotics in the
intensive care unit (ICU), making the ICU a true antibiotic hotspot. The increasing incidence …

Pros and cons of using biomarkers versus clinical decisions in start and stop decisions for antibiotics in the critical care setting

WC Albrich, S Harbarth - Intensive care medicine, 2015 - Springer
Introduction Patients in the intensive care unit (ICU) frequently receive prolonged or even
unnecessary antibiotic therapy, which selects for antibiotic-resistant bacteria. Over the last …

Antibiotic optimization in the intensive care unit

BD Lizza, N Raush, ST Micek - Seminars in Respiratory and …, 2022 - thieme-connect.com
Effective antimicrobial therapy remains paramount to successful treatment of patients with
critical illness, such as pneumonia and sepsis. Unfortunately, critically ill patients often …

[HTML][HTML] When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit

KJ Denny, J De Wale, KB Laupland, PNA Harris… - Clinical Microbiology …, 2020 - Elsevier
Background Most intensive care unit (ICU) patients receive broad-spectrum antibiotics.
While lifesaving in some, in others these treatments may be unnecessary and place patients …