The potential toxic effects of the metabotropic glutamate receptor agonist (1S, 3R)-1-
aminocyclopentane-1, 3-dicarboxylic acid (ACPD) and its interactions with the N-methyl-d …

Our recent study on ionotropic (±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid
(AMPA)/kainate (KA) type glutamate receptors in mouse spinal cord revealed differences …

Although cultured astrocytes express functional glutamate receptors, they are generally
resistant to excitotoxic cell death. We explored the role of receptor desensitization in …

1 A grease‐gap technique has been used to measure dc potentials, in response to the
application of excitatory amino acids and electrical stimulation of the Schaffer collateral …

Tosyl-polyamine derivatives such as N-{4-[4-(guanidinobutylamino)-butylamino] butyl}-4-
methylbenzenesulfonamide trihydrochroride (TsHSPMG) have been found to strongly inhibit …

Multiple sclerosis is an inflammatory disease of the CNS leading to the destruction of
oligodendrocytes (OLs), myelin sheaths and axons. The mediators of tissue injury remain …

Objectives Current research efforts are centered on delineating the novel health benefits of
naturally derived saccharides, including growing interest in their abilities to influence …

We investigated the role of desensitization of α‐amino‐3‐hydroxy‐5‐methyl‐isoxazole‐4‐
propionate (AMPA) receptors on the neurotoxicity and on the [Ca2+] i changes induced by …

The effect of sustained activation of excitatory amino acid receptors on neuronal survival
was studied using slices of adult rat hippocampus and light and electron microscopy …

Activity-dependent enduring change in cellular communication is essential for specific
connectivity during development of the nervous system and for adaptive responses of the …