Neurodegenerative diseases are intricate in nature because of the involvement of the
multiple pathophysiological events including mitochondrial dysfunction, neuroinflammation …

Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

The distinguishing pathogenic features of neurodegenerative diseases include
mitochondrial dysfunction and derived reactive oxygen species generation. The neural …

Alzheimer's disease (AD) is a neurodegenerative disorder which leads to mental
deterioration due to aberrant accretion of misfolded proteins in the brain. According to …

The overall aim of this article is to review current therapeutic strategies for treating AD, with a
focus on mitochondrially targeted antioxidant treatments. Recent advances in molecular …

Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …

Alzheimer's disease (AD), the most common form of dementia, has increasing incidence,
increasing mortality rates, and poses a huge burden on healthcare. None of the currently …

Mitochondria are complex, intercellular organelles present in the cells and are involved in
multiple roles including ATP formation, free radicals generation and scavenging, calcium …

Mitochondrial dysfunction and oxidative stress are two interdependent and reinforcing
damage mechanisms that play a central role in brain aging. Oxidative stress initiated and …